Which type of cell junction is primarily responsible for forming an impermeable barrier between epithelial cells, and how does it achieve this function?

• A. Desmosomes - By anchoring cells together with intermediate filaments
• B. Gap junctions - By allowing the passage of ions and small molecules between cells
• C. Tight junctions - By sealing the space between adjacent cells through transmembrane proteins such as claudins and occludins
• D. Adherens junctions - By connecting actin filaments between cells through cadherin proteins

Answer: (C)