Table of contents
- 1. Introduction to Genetics51m
- 2. Mendel's Laws of Inheritance3h 37m
- 3. Extensions to Mendelian Inheritance2h 41m
- 4. Genetic Mapping and Linkage2h 28m
- 5. Genetics of Bacteria and Viruses1h 21m
- 6. Chromosomal Variation1h 48m
- 7. DNA and Chromosome Structure56m
- 8. DNA Replication1h 10m
- 9. Mitosis and Meiosis1h 34m
- 10. Transcription1h 0m
- 11. Translation58m
- 12. Gene Regulation in Prokaryotes1h 19m
- 13. Gene Regulation in Eukaryotes44m
- 14. Genetic Control of Development44m
- 15. Genomes and Genomics1h 50m
- 16. Transposable Elements47m
- 17. Mutation, Repair, and Recombination1h 6m
- 18. Molecular Genetic Tools19m
- 19. Cancer Genetics29m
- 20. Quantitative Genetics1h 26m
- 21. Population Genetics50m
- 22. Evolutionary Genetics29m
21. Population Genetics
Allelic Frequency Changes
1:58 minutes
Problem 22b
Textbook Question
Textbook QuestionTay–Sachs disease is an autosomal recessive neurological disorder that is fatal in infancy. Despite its invariably lethal effect, Tay–Sachs disease occurs at very high frequency in some Central and Eastern European (Ashkenazi) Jewish populations. In certain Ashkenazi populations, 1 in 750 infants has Tay–Sachs disease. Population biologists believe the high frequency is a consequence of genetic bottlenecks caused by pogroms (genocide) that have reduced the population multiple times in the past several hundred years. In the population described, what is the frequency of the recessive allele that produces Tay–Sachs disease?
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