The frequencies of the four alleles contributed to the child by p...

Question

The frequencies of the four alleles contributed to the child by possible father F1 in Problem 7 are 0.18, 0.23, 0.13, and 0.14.

Calculate the Combined Paternity Index (CPI) for the four genes in this analysis.

Accepted Answer

Hi, everyone. Let's look at the next problem. It says consider the paternity index P I of the following markers that we have four different markers with four different P I values listed here. Then it says using the combined paternity index C P I, what is the probability that the person being investigated is the father of the child choice? A 99% or higher? B 50% C 25% or D 0%. Well, let's recall that we look at paternity indices. We are essentially talking about probabilities or frequencies. And because all of these markers independently assort we're talking about the probability of several different independent events having happening. So what's the probability of a particular alley being passed along to the child? So when you talk about the probability of multiple things happening, so all of these different alleys being inherited, that would be the product of the probability of the individual events all occurring. So again, to get that probability here, we'd want to multiply all of these individual paternity index values that we received to get this combined paternity index. So if we multiply all of these together 4.65, multiplied by 1.757, multiplied by 4.0, multiplied by 4.92. Our end result is 0.67. And that again would be our combined paternity index. Well, when we analyze those numbers, AC P I of greater than 100 equals a 99% or higher probability, that's the alleged father is the father. So when we go over here, that's our answer choice. A 99% or higher is what we're looking for to determine the probability that the person being investigated is the father of the child. With this calculated combined paternity index. See you in the next video.

The frequencies of the four alleles contributed to the child by possible father F1 in Problem 7 are 0.18, 0.23, 0.13, and 0.14. Calculate the Combined Paternity Index (CPI) for the four genes in this analysis.

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