Question

What is the statistical principle underlying genetic health risk assessment? Why are these assessments not predictive of disease occurrence?

Accepted Answer

Hi, everybody. Let's look at our next question. It is a measure of the risk of metabolic disorders such as diabetes and cardiovascular disease. Based on the combination of waist circumference and fasting tri triglyceride levels. Choice A lipid accumulation product index B discrimination index C combined DNA index system or D match index. Well, the measure of this risk of metabolic disorders based on waist circumference and fasting triglyceride levels is choice A the lipid accumulation product index, the higher that measure is the higher the risk of those card, those metabolic disorders occurring. Let's just look briefly at our other choices to understand why they're not correct. A discriminate. The discrimination index. Choice B is the ability of a statistical analysis to distinguish between two groups. So obviously not what we're talking about here. So that's why that's not our answer. So I see the combined DNA index system, hopefully, the fact it's got DNA DNA in there would help us to rule that out. And then the match index are both tools of forensic DNA analysis and both refer to the probability of a match between a DNA sample and a suspect or something from a database So definitely not what we're looking at here. So again, the measure of the risk of metabolic disorders among these choices here is choice, a lipid accumulation product index. See you in the next video.

What is the statistical principle underlying genetic health risk assessment? Why are these assessments not predictive of disease occurrence?

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