Concepts of Genetics, 12th Global Edition

New to this Edition

Keep Your Course Current and Relevant

• Two new Special Topics in Modern Genetics mini-chapters explore cutting-edge topics, including CRISPR-Cas and Genomic Editing and Advances in Neurogenetics: The Study of Huntington Disease.
  - All Special Topics chapters include a series of questions that help students review key ideas or facilitate personal contemplations and group discussions.
  - Assessment questions for Special Topics in Modern Genetics Chapters are assignable in Mastering Genetics.
• Reorganized and expanded coverage of gene regulation in eukaryotes reflects recent discoveries that reveal how RNA in many forms plays critical roles in the regulation of eukaryotic gene activity. A single chapter on this topic in previous editions has been expanded to three: Transcriptional Regulation in Eukaryotes (Chapter 17), Posttranscriptional Regulation in Eukaryotes (Chapter 18), and Epigenetics (Chapter 19).
• An increased emphasis on ethical considerations helps students think through ethical aspects of genetics-related issues. Essays that used to be known as Genetics, Technology, and Society have been replaced or revised as Genetics, Ethics, and Society. In addition, each chapter ends with a Case Study, each of which raises ethical questions.
• Modern Approaches to Understanding Gene Function feature challenges students to understand how modern gene targeting approaches (such as the use of transgenic animals, knockout animals, and RNA interference) have dramatically advanced our understanding of gene function. Each entry highlights representative experimental approaches, analyzes experimental data, and relates to a concept discussed in the chapter. Each feature includes questions for further analysis or discussion.

Motivate Students to Develop and Practice Problem-solving Skills

• Updated! Mastering Genetics is an online homework and assessment program that guides students through complex topics in genetics, using in-depth tutorials that coach students to correct answers with hints and feedback specific to their misconceptions and errors. See “Personalize Learning with Mastering Genetics.”
• Now Solve ThisProblems are integrated throughout each chapter to test student knowledge while learning chapter content. Exercises include a hint to guide students and a brief answer is provided in the appendix. One Now Solve This problem per chapter is linked to related end of chapter problems to make it easier for professors to assign similar problems for homework.
• Insights and Solutions sections strengthen students’ problem solving skills by showing step-by-step solutions and rationales for select problems.
• Problems and Discussion Questions are found at the end of every chapter and most are assignable in Mastering Genetics.
• Extra Spicy Problems challenge students to solve complex problems, many based on data derived from primary genetics literature.
• How Do We Know? questions appear as the first entry in the Problems and Discussion Questions and ask students to identify the experimental basis underlying important concepts and conclusions—that is, how we know what we know. Students are asked to review numerous findings discussed in the chapter and to summarize the process of discovery that was involved.   

Emphasize the Fundamental Ideas of Genetics

• A Concept Question, found as the second question in the Problems and Discussion Questions, asks the student to review and comment on common aspects of the Key Concepts listed at the beginning of each chapter. This feature places added emphasis on the pedagogic approach of conceptual learning.
• Evolving Concept of the Gene is a short feature, integrated in appropriate chapters, that highlights how scientists’ understanding of what a gene is has changed over time. Since we cannot see genes, we must infer just what this unit of heredity is, based on experimental findings. By highlighting how scientists’ conceptualization of the gene has advanced over time, this feature helps students appreciate the process of discovery that has led to an even more sophisticated understanding of hereditary information.
  
  

Engage Students in Active and Cooperative Learning

• NEW! Genetics, Ethics, and Society essays provide a synopsis of an ethical issue related to a current finding in genetics that impacts directly on society today. It includes a section called Your Turn, which directs students to related resources of short readings and websites to support deeper investigation and discussion of the main topic of each essay.
• Case studies at the end of each chapter have been updated with new topics. Students can read and answer questions about a short scenario related to one of the chapter topics. The Case Studies link the coverage of formal genetic knowledge to everyday societal issues, and they include ethical considerations.
• Exploring Genomics boxes help students apply genetics to modern techniques such as genomics, bioinformatics, and proteomics. These boxes illustrate how genomic studies have an impact on every aspect of genetics. Exercises provide thoughtful questions and direct students to related online resources, allowing them to increase their awareness of genomics.
  
  

Mastering Geneticsis not included.

Students, if Mastering Genetics is a recommended/mandatory component of the course, please ask your instructor for the correct ISBN. Mastering Genetics should only be purchased when required by an instructor. Instructors, contact your Pearson representative for more information.

• NEW! Dynamic Study Modules (DSMs) help students study effectively on their own by continuously assessing their performance in real time and adapting to their level of understanding. Students complete a set of questions with a unique answer format that also asks them to indicate their confidence level in their answer. Questions repeat until the student can answer them all correctly and confidently. These are available as graded assignments prior to class or as self-study tools for students. They are accessible on smartphones, tablets, and computers. Instructors can delete questions from Dynamic Study Modules to better fit their course.
• A library of 104 Practice Problems offers more opportunities to assign high quality problems for student homework or practice. These questions appear only in Mastering Genetics and include targeted wrong-answer feedback to help students learn from their mistakes.
• More than 120 activities and in-depth tutorials, focused on key genetics concepts, reinforce problem-solving skills with hints and feedback specific to students’ misconceptions and errors. Tutorial topics include pedigree analysis, sex linkage, gene interactions, DNA replication, and more.
• Approximately 90% of end-of-chapter questions are available for auto-graded homework assignments. To prepare students for the challenging problems that they are likely to see on exams, question types include sorting, labeling, entering numerical information, multiple choice, and fill-in-the-blank.
• 24/7 Coaching in Solving Genetics Problems give students access hints to get back on track at the moment when they get stuck. If an incorrect answer is submitted, Mastering Genetics gives instant feedback specific to the error made, helping students overcome misconceptions and strengthen problem-solving skills.
• Assessment questions for Special Topics in Modern Genetics Chapters are assignable in the Mastering Genetics item library.
• Learning Catalytics™ helps generate class discussion, customize lectures, and promote peer-to-peer learning with real-time analytics.Learning Catalytics acts as a student response tool that uses students’ smartphones, tablets, or laptops to engage them in more interactive tasks and thinking.

 

• Help your students develop critical thinking skills.
• Monitor responses to find out where your students are struggling.
• Rely on real-time data to adjust your teaching strategy.
• Automatically group students for discussion, teamwork, and peer-to-peer learning.

Upload a full PowerPoint® deck to easily create slide questions.

Table of Contents

 

Part One--Genes, Chromosomes, and Heredity

1 Introduction to Genetics

2 Mitosis and Meiosis

3 Mendelian Genetics

4 Extensions of Mendelian Genetics

5 Sex Determination and Sex Chromosomes

6 Chromosomal Mutations: Variation in Number and Arrangement

7 Chromosome Mapping in Eukaryotes

8 Genetic Analysis and Mapping in Bacteria and Bacteriophages

9 Extranuclear Inheritance

Part Two--DNA: Structure, Replication, and Organization

10 DNA Structure and Analysis

11 DNA Replication and Recombination

12 DNA Organization in Chromosomes

Part Three--Gene Expression and Its Regulation

13 The Genetic Code and Transcription

14 Translation and Proteins

15 Gene Mutation, DNA Repair, and Transposition

16 Regulation of Gene Expression in Bacteria

17 Transcriptional Regulation in Eukaryotes

18 Posttranscriptional Regulation in Eukaryotes

19 Epigenetic Regulation of Gene Expression

Part Four--Genomics

20 Recombinant DNA Technology

21 Genomic Analysis

22 Applications of Genetic Engineering and Biotechnology

Part Five--Genetics of Organisms and Populations

23 Developmental Genetics

24 Cancer Genetics

25 Quantitative Genetics and Multifactorial Traits

26 Population and Evolutionary Genetics

Special Topics in Modern Genetics

ST1 CRISPR and Genome Editing

ST2 DNA Forensics

ST3 Genomics and Precision Medicine

ST4 Genetically Modified Foods

ST5 Gene Therapy

ST6 Advances in Neurogenetics: The Study of Huntington Disease

Appendix A Selected Readings

Appendix B Answers to Selected Problems

Mastering Biology

This title can be supported by MyLab Biology, an online homework and tutorial system, designed to test and build your students understanding. If you'd like to arrange a demonstration of MyLab Biology, let us know by contacting us at docent@pearson.com and we can get a Pearson representative to contact you. Visit Pearson MyLab & Mastering to find out how it can improve results by engaging students effectively with immersive content, tools, and experiences.

 

Packages

Pearson offers special pricing when you choose to package your text with other student resources. If you're interested in creating a cost-saving package for your students, browse our available packages below, or contact your Pearson Account Manager to create your own package.

Concepts of Genetics plus Pearson MasteringGenetics with Pearson eText, Global Edition, 12th Edition

William Klug, Michael Cummings, Charlotte Spencer, Michael Palladino, Darrell Killian

Valuepack ISBN13: 9781292265537 | ISBN10: 1292265531
Available: Jun 2019

Downloadable Instructor Resources

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Instructor Resource Materials for Concepts of Genetics, Global Edition, 12/E

Klug, Cummings, Spencer, Palladino & Killian

ISBN-13: 9781292265469

©2020 • Online • Live

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TestGen for Concepts of Genetics, Global Edition, 12/E

Klug, Cummings, Spencer, Palladino & Killian

ISBN-13: 9781292265520

©2020 • Online • Live

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Please note:The PC and MAC versions of this testbank file must be used in conjunction with Pearson's TestGen application. Go to the TestGen website to download software, upgrade, and access "getting started" TestGen resources.