Becker's World of the Cell, 10th edition

  • Jeff Hardin, 
  • Greg Bertoni

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Becker’s World of the Cell provides a beautifully illustrated, up-to-date introduction to cell biology concepts, processes, and applications. The text features descriptions of all major principles with unique scientific insights into visualization and applications of cell and molecular biology.

Published by Pearson (June 25th 2021) - Copyright © 2022

ISBN-13: 9780137441778

Subject: Biology

Category: Cell Biology

Table of contents


1. A Preview of Cell Biology
2. The Chemistry of the Cell
3. The Macromolecules of the Cell
4. Cells and Organelles
5. Bioenergetics: The Flow of Energy in the Cell
6. Enzymes: The Catalysts of Life
7. Membranes: Their Structure, Function, and Chemistry
8. Transport Across Membranes: Overcoming the Permeability Barrier
9. Chemotrophic Energy Metabolism: Glycolysis and Fermentation
10. Chemotrophic Energy Metabolism: Aerobic Respiration
11. Phototrophic Energy Metabolism: Photosynthesis
12. The Endomembrane System
13. Cytoskeletal Systems
14. Cellular Movement: Motility and Contractility
15. Beyond the Cell: Cell Adhesions, Cell Junctions, and Extracellular Structures
16. The Structural Basis of Cellular Information: DNA, Chromosomes, and the Nucleus 
17. DNA Replication, Repair, and Recombination
18. Gene Expression I: The Genetic Code and Transcription
19. Gene Expression II: Protein Synthesis and Sorting
20. The Regulation of Gene Expression
21. Molecular Biology Techniques for Cell Biology
22. Signal Transduction Mechanisms I: Electrical and Synaptic Signaling in Neurons
23. Signal Transduction Mechanisms II: Messengers and Receptors
24. The Cell Cycle and Mitosis
25. Sexual Reproduction, Meiosis, and Genetic Recombination
26. Cancer Cells
Appendix: Visualizing Cells and Molecules


Key Technique

Chapter 1: Using Immunofluorescence to Identify Specific Cell Components
Chapter 2: Determining the Chemical Fingerprint of a Cell Using Mass Spectrometry
Chapter 3: Using X-ray Crystallography to Determine Protein Structure
Chapter 4: Using Centrifugation to Isolate Organelles
Chapter 5: Measuring How Molecules Bind One Another Using Isothermal Titration Calorimetry
Chapter 6: Determining Km and Vmax Using Enzyme Assays
Chapter 7: SDS–Polyacrylamide Gel Electrophoresis (SDS-PAGE) of Membrane Proteins
Chapter 8: Expression of Heterologous Membrane Proteins in Frog Oocytes
Chapter 9: Using Isotopic Labeling to Determine the Fate of Atoms in a Metabolic Pathway
Chapter 10: Visualizing Cellular Structures with Three-Dimensional Electron Microscopy
Chapter 11: Determining Absorption and Action Spectra via Spectrophotometry
Chapter 12: Visualizing Vesicles at the Cell Surface Using Total Internal Reflection Microscopy (TIRF)
Chapter 13: Studying the Dynamic Cytoskeleton
Chapter 14: Watching Motors Too Small to See
Chapter 15: Building an ECM from Scratch
Chapter 16: FISHing for Specific Sequences
Chapter 17: The Polymerase Chain Reaction
Chapter 18: Hunting for DNA-Protein Interactions
Chapter 19: Protein Localization Using Fluorescent Fusion Proteins
Chapter 20: Gene Knockdown via RNAi
Chapter 21: DNA Cloning
Chapter 22: Patch Clamping
Chapter 23: Calcium Indicators and Ionophores
Chapter 24: Measuring Cells Millions at a Time (FACS ­Analysis)
Chapter 25: Using Mendel's Rules to Predict Human Disease
Chapter 26: "Rational" Drugs in the Fight Against Cancer

Human Connections

Chapter 1: The Immortal Cells of Henrietta Lacks (The origin of the first human cultured cell line)
Chapter 2: Taking a Deeper Look -- Magnetic Resonance Imaging (MRI) (How an MRI can image human tissues)
Chapter 3: Aggregated Proteins and Alzheimer Disease (Protein misfolding and human disease)
Chapter 4: When Cellular "Breakdown" Breaks Down (Diseases caused by lysosome dysfunction)
Chapter 5: The "Potential" of Food to Provide Energy (Calorie contents of foods)
Chapter 6: ACE Inhibitors: Enzyme Activity as the Difference Between Life and Death (Blood pressure medication based on snake venom)
Chapter 8: Membrane Transport, Cystic Fibrosis, and the Prospects for Gene Therapy
Chapter 9: What Happens to the Sugar? (Dietary food intake and metabolism)
Chapter 10: A Diet Worth Dying For? (The dangers of using uncouplers such as DNP to lose weight)
Chapter 11: How Do Plants Put on Sunscreen? (How the plant xanthophyll cycle dissipates excess solar energy)
Chapter 12: It's All in the Family (LDL receptors, cholesterol uptake, hypercholesterolemia)
Chapter 13: When Actin Kills (Listeria infection and actin polymerization)
Chapter 14: Dyneins Help Us Tell Left from Right (Motors and left-right axis specification)
Chapter 15: The Costly Effects of Weak Adhesion (Blistering diseases of the skin)
Chapter 16: Lamins and Premature Aging (Progeria and the nuclear envelope)
Chapter 17: Children of the Moon (Xeroderma pigmentosum and DNA repair)
Chapter 19: To Catch a Killer: The Problem of Antibiotic Resistance in Bacteria
Chapter 20: The Epigenome: Methylation and Disease (Rett syndrome and imprinting disorders)
Chapter 21: More Than Your Fingertips: Identifying Genetic "Fingerprints" (STRs in genetic identification)
Chapter 22: In the Search for the Fountain of Youth, Are People Paying for Poison? (Cosmetic uses of Botulinum toxin)
Chapter 23: How to Prevent a Heart Attack (Nitric oxide ­signaling and vasoconstriction)
Chapter 24: What do Ethnobotany and Cancer Have in Common? (Taxol and cancer treatment)
Chapter 25: When Meiosis Goes Awry (Down syndrome and nondisjunction)
Chapter 26: Molecular Sleuthing in Cancer Diagnosis (Molecular analysis of breast cancer)

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