Overview
Description
This print textbook is available for students to rent for their classes. The Pearson print rental program provides students with affordable access to learning materials, so they come to class ready to succeed.
For courses in general microbiology.
Authoritative. Accurate. Accessible
Brock Biology of Microorganisms sets the standard for accuracy, impeccable scholarship, a visually stunning art program, and the use of cutting edge research to illustrate basic concepts. The text guides students through the six major themes of microbiology – Evolution, Cell Structure and Function, Metabolic Pathways, Information Flow and Genetics, Microbial Systems, and the Impact of Microorganisms – as outlined by the American Society for Microbiology Conference on Undergraduate Education (ASMCUE). This robust and modern approach takes students through the genomics revolution and “omics” maze that has transformed microbiology and shares powerful tools that microbiologists use to probe deeper and further into the microbial world than ever before.
The 16th Edition expands the extraordinary art program to ensure students experience microbiology as a visual science while providing an overview of the microbial world with basic principles that students all need to master. Each chapter’s theme focuses on a recent discovery that connects students with the most current science and engages them with exciting, real-world topics.
Now available with Modified Mastering Microbiology
Mastering™ is the teaching and learning platform that empowers you to reach every student. By combining trusted author content with digital tools developed to engage students and emulate the office-hour experience, Mastering personalizes learning and improves results for each student. Mastering Microbiology extends learning and provides students with a platform to practice, learn, and apply knowledge outside of the classroom. Learn more about Mastering Microbiology.
Preface
Preface is available for download in PDF format.
This material is protected under all copyright laws, as they currently exist. No portion of this material may be reproduced, in any form or by any means, without permission in writing from the publisher.
Features
Making connections across concepts in microbiology
- NEW - Key Concept statements at the start of each major part of a chapter give students a big picture view of the content before they dive in and immerse themselves in the details.
- NEW - References back to content earlier in the text in every chapter, remind students what they learned in earlier chapters so they better understand what they are learning now.
- NEW - Additional Explore the Microbial World features give students a feel for special topics in Microbiology and fuel their curiosity.
- Evolution as a Framework uses evolution as an overarching theme to unite microbiological concepts and provide a framework upon which students can build their knowledge.
Current coverage of the science of molecular biology and the genomic revolution
- NEW - 34 MicrobiologyNow chapter-opening vignettes created for this edition introduce each chapter’s theme through a recent discovery in the field of microbiology. These exciting accounts draw students into the chapter and show how the chapter content connects with real world problems. Assignable MicrobiologyNow coaching activities are available in Mastering Microbiology.
- NEW - Immunotherapy section covers the hottest thing in cancer treatment and related therapeutic medicine today with an emphasis on new discussion of the likely links between disorders of the microbiome and specific syndromes.
- NEW - Chapter on the human microbiome now includes a new section on the human virome, describing how metagenomics is aiding the discovery and isolation of many new viruses. Extensive coverage is provided of the impact of early life events on the development of the newborn gut microbiome and of recent successes in probiotic therapy for preventing newborn intestinal diseases.
- UPDATED - 21st Century Microbiology content covers global climate change, biofuels, and microbial fuel cells.
Deepen student understanding of the microbial world
- NEW - Stunningly visual introductory chapter on viruses in Unit I (The Foundations of Microbiology) bolsters and completes the overview of the microbial world with basic principles of microbiology that all students need to master.
- Molecular Microbiology and Immunology chapters deepen discussion of eukaryotic and archaeal genetics and reflects the relatedness of genetic information flow. A streamlined discussion of immunity with enhanced detail between innate and adaptive linkages helps students grasp the complexity and specificity of immune responses.
Now available with Modified Mastering Microbiology
Mastering™ is the teaching and learning platform that empowers you to reach every student. By combining trusted author content with digital tools developed to engage students and emulate the office-hour experience, Mastering personalizes learning and improves results for each student. Mastering Microbiology extends learning and provides students with a platform to practice, learn, and apply knowledge outside of the classroom. Learn more about Mastering Microbiology.
Teach your course your way: Your course is unique. So whether you’d like to build your own auto-graded assignments, foster student engagement during class, or give students anytime, anywhere access, Mastering gives you the flexibility to easily create your course to fit your needs.
- Dynamic Study Modules are assignable modules that pose a series of question sets about a course topic. The questions adapt to each student’s performance and offer personalized, targeted feedback to help them master key concepts. As a result, students build the confidence they need to deepen their understanding, participate meaningfully, and perform better – in and out of class. Students can use their computer or the MyLab and Mastering app to access Dynamic Study Modules. Available for select titles.
- With Learning Catalytics, you’ll hear from every student when it matters most. You pose a variety of questions that help students recall ideas, apply concepts, and develop critical-thinking skills. Your students respond using their own smartphones, tablets, or laptops. You can monitor responses with real-time analytics and find out what your students do – and don’t – understand. Then, you can adjust your teaching accordingly, and even facilitate peer-to-peer learning, helping students stay motivated and engaged.
Empower each learner: Each student learns at a different pace. Personalized learning, including adaptive tools and wrong-answer feedback, pinpoints the precise areas where each student needs practice and gives all students the support they need – when and where they need it – to be successful.
- NEW - Pearson eText is a simple-to-use, mobile-optimized, personalized reading experience available within Mastering. It allows students to easily highlight, take notes, and review key vocabulary all in one place–even when offline. Seamlessly integrated videos and other rich media engage students and give them access to the help they need, when they need it.
- NEW - MicrobiologyNow Coaching Activities correlate with each chapter-opening vignette that introduced each chapter’s theme through a recent discovery in the field of microbiology and can be assigned in Mastering Microbiology.
- MicroCareers Coaching Activities provide students an opportunity to investigate microbiology principles and diseases from the perspective of various careers.
- Clinical Case Study Coaching Activities help students connect microbiological theory to real-world diagnosis and treatment, allowing them to put their knowledge into practice and think like a nurse.
- ASM Curriculum Guidelines pre-test and post-test assessments are assignable in Mastering Microbiology for efficient and customizable assessment of the six underlying concepts and 22 related topics of lasting importance as determined by the American Society of Microbiology.
- MCAT prep questions emulate the appropriate content sections, cognitive skills, and question types of the MCAT for which many students are preparing to sit.
Deliver trusted content: We partner with highly respected authors to develop interactive content and course-specific resources that keep students on track and engaged.
- Interactive Microbiology is a dynamic suite of interactive tutorials and animations that teach key microbiology concepts including Operons, Biofilms and Quorum Sensing, Complement, Human Microbiota, and Antibiotic Resistance. Interactive Microbiology actively engages students with each topic, enabling them to learn from manipulating variables, predicting outcomes, and answering formative and summative assessment questions. Each tutorial presents the concept within a real healthcare scenario in order to emphasize problem solving and interest students from the beginning.
- Microboosters offer a mobile friendly way for students to review (or learn for the first time) foundational concepts that are important in order to understand microbiology. Topics included are Study Skills, General and Organic Chemistry, Cell Biology and more. These activities can be assigned through Mastering Microbiology and are available for self-study through Dynamic Study Modules.
- MicroLab Tutors prepare students for their labs by introducing and assessing their understanding of the most important lab concepts and techniques. When appropriate, molecular animations combine with the lab technique to help visualize lecture concepts. Tutorials provide visual and answer-specific feedback to coach students in how to interpret and analyze different lab results.
- Videos and Animations can be assigned in Mastering A&P.
- Lab Technique Videos give students an opportunity to see techniques performed correctly and quiz themselves on lab procedures before and after lab time.
- MicroFlix™ 3D movie-quality animations help your students visualize complex microbiology topics the three toughest topics in microbiology: metabolism, DNA replication, and immunology. The animations include automatically graded coaching activities with personalized feedback and hints.
- BioFlix™ 3D movie-quality animations help your students visualize complex biology topics and include automatically graded coaching activities with personalized feedback and hints.
- Microbe at a Glance Coaching Activities require students to recognize and sort diseases by different categories (transmission type, pathogenesis, signs and symptoms, associated organisms, treatment, etc.). Coaching activities allow instructors to assess students’ understanding and recognition of important diseases.
Improve student results: When you teach with Mastering, student performance often improves. That’s why instructors have chosen Mastering for over 15 years, touching the lives of over 20 million students.
Check out the preface for a complete list of features and what's new in this edition.
New to This Edition
- Key Concept statements at the start of each major part of a chapter give students a big picture view of the content before they dive in and immerse themselves in the details.
- References back to content earlier in the text in every chapter, remind students what they learned in earlier chapters so they better understand what they are learning now.
- Additional Explore the Microbial World features give students a feel for special topics in Microbiology and fuel their curiosity.
Current coverage of the science of molecular biology and the genomic revolution
- 34 MicrobiologyNow chapter-opening vignettes created for this edition introduce each chapter’s theme through a recent discovery in the field of microbiology. These exciting accounts draw students into the chapter and show how the chapter content connects with real world problems. Assignable MicrobiologyNow coaching activities are available in Mastering Microbiology.
- Immunotherapy section covers the hottest thing in cancer treatment and related therapeutic medicine today with an emphasis on new discussion of the likely links between disorders of the microbiome and specific syndromes.
- Chapter on the human microbiome now includes a new section on the human virome, describing how metagenomics is aiding the discovery and isolation of many new viruses. Extensive coverage is provided of the impact of early life events on the development of the newborn gut microbiome and of recent successes in probiotic therapy for preventing newborn intestinal diseases.
- UPDATED - 21st Century Microbiology content covers global climate change, biofuels, and microbial fuel cells.
Deepen student understanding of the microbial world
- Stunningly visual introductory chapter on viruses in Unit I (The Foundations of Microbiology) bolsters and completes the overview of the microbial world with basic principles of microbiology that all students need to master.
Now available with Modified Mastering Microbiology
Mastering™ is the teaching and learning platform that empowers you to reach every student. By combining trusted author content with digital tools developed to engage students and emulate the office-hour experience, Mastering personalizes learning and improves results for each student. Mastering Microbiology extends learning and provides students with a platform to practice, learn, and apply knowledge outside of the classroom. Learn more about Mastering Microbiology.
- Pearson eText is a simple-to-use, mobile-optimized, personalized reading experience available within Mastering. It allows students to easily highlight, take notes, and review key vocabulary all in one place—even when offline. Seamlessly integrated videos and other rich media engage students and give them access to the help they need, when they need it.
- MicrobiologyNow Coaching Activities correlate with each chapter-opening vignette that introduced each chapter’s theme through a recent discovery in the field of microbiology and can be assigned in Mastering Microbiology.
Table of Contents
UNIT 1: THE FOUNDATIONS OF MICROBIOLOGY
1. The Microbial World
2. Microbial Cell Structure and Function
3. Microbial Metabolism
4. Microbial Growth and Its Control
5. Viruses and Their Multiplication
UNIT 2: MOLECULAR BIOLOGY AND GENETICS
6. Microbial Information Flow and Protein Processing
7. Microbial Regulatory Systems
8. Molecular Aspects of Microbial Growth
9. Genetics of Bacteria and Archaea
UNIT 3: GENOMICS, SYNTHETIC BIOLOGY, AND EVOLUTION
10. Microbial Genomics and Other Omics
11. Viral Genomics and Diversity
12. Biotechnology and Synthetic Biology
13. Microbial Evolution and Genome Dynamics
UNIT 4: MICROBIAL DIVERSITY
14. Metabolic Diversity of Microorganisms
15. Ecological Diversity of Bacteria
16. Phylogenetic Diversity of Bacteria
17. Phylogenetic Diversity of Archaea
18. Diversity of Microbial Eukarya
UNIT 5: MICROBIAL ECOLOGY AND ENVIRONMENTAL MICROBIOLOGY
19. Taking the Measure of Microbial Systems
20. Microbial Ecosystems
21. Nutrient Cycles
22. Microbiology of the Built Environment
23. Microbial Symbioses with Microbes, Plants, and Animals
UNIT 6: MICROBE—HUMAN INTERACTIONS AND THE IMMUNE SYSTEM
24. Microbial Symbioses with Humans
25. Microbial Infection and Pathogenesis
26. Innate Immunity: Broadly Specific Host Defenses
27. Adaptive Immunity: Highly Specific Host Defenses
28. Immune Disorders and Antimicrobial Therapy
UNIT 7: INFECTIOUS DISEASES
29. Diagnosing Infectious Diseases
30. Epidemiology and Public Health
31. Person-to-Person Bacterial and Viral Diseases
32. Vectorborne and Soilborne Bacterial and Viral Diseases
33. Waterborne and Foodborne Bacterial and Viral Diseases
34. Eukaryotic Pathogens: Fungi, Protozoa, and Helminths
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About the Author(s)
About our authors
Michael T. Madigan received his B.S. in Biology and Education from Wisconsin State UniversityStevens Point (1971) and his M.S. (1974) and Ph.D. (1976) in Bacteriology from the University of WisconsinMadison in the laboratory of Thomas Brock. Following a postdoc at Indiana University with Howard Gest, Mike moved to Southern Illinois University Carbondale, where he taught courses in introductory microbiology and bacterial diversity as a professor of microbiology for 33 years. In 1988 Mike was selected as the Outstanding Teacher in the College of Science and in 1993, the Outstanding Researcher. In 2001 he received the SIUC Outstanding Scholar Award and Distinguished Professor title. In 2003 Mike received the Carski Award for Distinguished Undergraduate Teaching from the American Society for Microbiology, and he is an elected Fellow of the American Academy of Microbiology. He has also been recognized by the American Red Cross as a major volunteer blood donor for the 24 gallons of blood he has donated since 1967. Mikes research is focused on phototrophic bacteria that inhabit extreme environments, and for the past 20 years his emphasis has been Antarctic microbiology. Mike has co-edited a major treatise on phototrophic bacteria and served for 10 years as chief editor of the journal Archives of Microbiology. He currently serves on the editorial board of the journals Environmental Microbiology and Antonie van Leeuwenhoek. Mikes other interests include forestry, swimming, reading, and caring for his dogs and horses. He lives on a small farm near a quiet lake with his wife, Nancy, three dogs (Kato, Nut, and Merlyn), and three horses (Eddie, Georgie, and Roscoe).
Kelly S. Bender received her B.S. in Biology from Southeast Missouri State University (1999) and her Ph.D. (2003) in Molecular Biology, Microbiology, and Biochemistry from Southern Illinois University Carbondale. Her dissertation research focused on the genetics of perchlorate-reducing bacteria. During her postdoctoral fellowship, Kelly worked on the genetic regulation of sulfate-reducing bacteria in the laboratory of Judy Wall at the University of MissouriColumbia. She also completed a transatlantic biotechnology fellowship at Uppsala University in Sweden researching regulatory small RNAs in bacteria. In 2006, Kelly returned to her alma mater, Southern Illinois University Carbondale, as an Assistant Professor in the Department of Microbiology and in 2012 was tenured and promoted to Associate Professor. She has served as Chair of the SIUC Department of Microbiology since 2018. Her lab studies a range of topics including regulation in sulfate-reducing bacteria, the microbial community dynamics of sites impacted by acid mine drainage, and diversity of phototrophic heliobacteria. Kelly teaches courses in introductory microbiology and microbial diversity, has served on numerous federal grant review panels, and is an active member of the American Society for Microbiology (ASM). Her other interests include spending time with her daughter, Violet, and husband, Dick.
Daniel H. Buckley is a Professor at Cornell University in the School of Integrative Plant Science and the Department of Microbiology. He earned his B.S. in Microbiology (1994) at the University of Rochester and his Ph.D. in Microbiology (2000) at Michigan State University. His graduate research in the laboratory of Thomas M. Schmidt explored environmental factors that influence microbial diversity in soils. Dan then received a National Science Foundation Postdoctoral Fellowship to work with Pieter T. Visscher, University of Connecticut, investigating linkages between microbial diversity and biogeochemistry within microbial mats and stromatolites. Dan moved to Cornell in 2003 where he investigates the ecology and evolution of the diverse microorganisms that live in soils. He has taught both introductory and advanced courses in microbiology, microbial diversity, and microbial genomics. He received a National Science Foundation Faculty Early Career Development (CAREER) award in 2005 for excellence in integrating research and education, and served as Co-Director of the MBL Microbial Diversity summer course in Woods Hole, Massachusetts (20092013). He currently serves on the editorial boards of Applied and Environmental Microbiology and Environmental Microbiology. Dan lives in Ithaca, New York, with his wife, Merry, and sons, Finn and Colin.
Matthew Sattley received his B.A. in Biology in 1998 from Blackburn College (Illinois) and his Ph.D. (2006) in Molecular Biology, Microbiology, and Biochemistry from Southern Illinois University Carbondale. His graduate studies focused on the microbiology of sulfur cycling and other biogeochemical processes in permanently ice-covered lakes of Antarctica. In his postdoctoral research at Washington University in Saint Louis, he studied the physiology and genomics of anoxygenic phototrophic bacteria in Robert Blankenships laboratory. Matt then accepted a faculty appointment to the Department of Biology at MidAmerica Nazarene University (Kansas), where he supervised undergraduate research and taught courses in microbiology, environmental science, and cell biology. In 2010, Matt transitioned to the Division of Natural Sciences at Indiana Wesleyan University (IWU), where he is a Professor of Biology and has served as the Director of the Hodson Summer Research Institute, a faculty-led summer research program for undergraduate students in the Natural Sciences. Matts research group investigates the ecology, diversity, and genomics of bacteria that inhabit extreme environments, and in 2017, he was the recipient of IWUs Outstanding Scholarship Award. Matt is a member of the American Society for Microbiology (including its Indiana Branch) and the Indiana Academy of Science. Matt lives in Marion, Indiana, with his wife, Ann, and sons, Josiah and Samuel. Outside of teaching and research, Matt enjoys playing drums, reading, motorcycling, and baseball.
David A. Stahl received his B.S. degree in Microbiology from the University of Washington, Seattle, and completed graduate studies in microbial phylogeny and evolution with Carl Woese in the Department of Microbiology at the University of Illinois at UrbanaChampaign. Subsequent work as a postdoctoral fellow with Norman Pace, then at the National Jewish Hospital in Colorado, involved early applications of 16S rRNA-based sequence analysis to the study of natural microbial communities. In 1984 Dave joined the faculty at the University of Illinois with appointments in Veterinary Medicine, Microbiology, and Civil Engineering. In 1994 he moved to the Department of Civil Engineering at Northwestern University, and in 2000 returned to the University of Washington as professor in the Departments of Civil and Environmental Engineering and Microbiology. Dave is known for his work in microbial evolution, ecology, and systematics, and received the 1999 Bergey Award and the 2006 ASM Procter & Gamble Award in Applied and Environmental Microbiology. Dave is an elected fellow of the American Academy of Microbiology and a member of the National Academy of Engineering. His main research interests surround the biogeochemistry of nitrogen and sulfur and the microbial communities that sustain the associated nutrient cycles. His laboratory was the first to culture ammonia-oxidizing Archaea, a group believed to be the key mediators of this process in the nitrogen cycle. Dave has taught several courses in environmental microbiology, was one of the founding editors of the journal Environmental Microbiology, and has served on many advisory committees. Outside the lab, Dave enjoys hiking, bicycling, spending time with family, reading a good science fiction book, andwith his wife, Linrenovating an old farmhouse on Bainbridge Island.
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