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Natural Killer Cells quiz

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  • Which statement about natural killer (NK) cells is false?
    A) NK cells are part of adaptive immunity
  • What type of immunity are natural killer cells a part of?
    Natural killer cells are part of innate immunity.
  • How do NK cells recognize infected host cells?
    NK cells recognize infected host cells by identifying irregular patterns such as the absence of MHC class I molecules.
  • What substances do NK cells release to induce apoptosis?
    NK cells release cytotoxic substances like perforin and protease-containing granules to induce apoptosis.
  • What is the role of perforin released by NK cells?
    Perforin creates pores in the membrane of the infected host cell, facilitating apoptosis.
  • What is antibody-dependent cellular cytotoxicity (ADCC)?
    ADCC is a process where NK cells bind to the Fc region of IgG antibodies on infected cells, leading to apoptosis.
  • How do viruses interfere with NK cell recognition?
    Viruses can interfere with antigen presentation, leading to the absence of MHC class I molecules on infected cells.
  • What is the significance of the Fc region in NK cell function?
    The Fc region of IgG antibodies allows NK cells to recognize and bind to infected cells, initiating ADCC.
  • Can NK cells interact with components of adaptive immunity?
    Yes, NK cells can interact with components of adaptive immunity, such as IgG antibodies, to enhance their function.