Review of Cytotoxic vs Helper T Cells definitions Flashcards
Review of Cytotoxic vs Helper T Cells definitions
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Cytotoxic T cellsImmune cells with CD8 markers that recognize antigens on MHC class 1 molecules and induce apoptosis in infected cells.Helper T cellsImmune cells with CD4 markers that recognize antigens on MHC class 2 molecules and activate other immune cells.MHC class 1 moleculesProteins found on all nucleated cells that present endogenous antigens to cytotoxic T cells.MHC class 2 moleculesProteins found on antigen presenting cells that present exogenous antigens to helper T cells.Antigen presenting cellsCells like dendritic cells, macrophages, and B cells that display antigens on MHC class 2 molecules.Endogenous antigensAntigens originating inside a target cell, often from intracellular pathogens like viruses.Exogenous antigensAntigens originating outside a target cell, processed and presented by antigen presenting cells.ApoptosisProgrammed cell death induced by cytotoxic T cells to eliminate infected host cells.CD8 markerSurface protein on cytotoxic T cells that allows recognition of MHC class 1 molecules.CD4 markerSurface protein on helper T cells that allows recognition of MHC class 2 molecules.Immune responseThe body's defense mechanism activated by harmful antigens to eliminate pathogens.T lymphocytesWhite blood cells that play a central role in cell-mediated immunity, including cytotoxic and helper T cells.Dendritic cellsAntigen presenting cells that process antigens and present them to T cells to initiate an immune response.MacrophagesAntigen presenting cells that engulf pathogens and present antigens to helper T cells.B cellsLymphocytes that can present antigens to helper T cells and produce antibodies as part of the immune response.