Structure and function of arteries, arterioles, capillaries, venules, and veins
Arteries carry blood away from the heart; arterioles regulate blood flow into capillaries; capillaries allow exchange of gases and nutrients; venules collect blood from capillaries; veins return blood to the heart.
Processes of capillary exchange
Capillary exchange occurs via diffusion, transcytosis, and bulk flow between blood and interstitial fluid.
Factors regulating blood flow volume and velocity
Blood flow is regulated by vessel diameter, blood pressure, blood viscosity, and total vessel length.
Mean arterial pressure (MAP) and systemic vascular resistance (SVR)
MAP is the average arterial pressure during a cardiac cycle; SVR is the resistance offered by systemic blood vessels affecting blood pressure.
Relationship between cross-sectional area and velocity of blood flow
As total cross-sectional area increases (e.g., in capillaries), blood velocity decreases, allowing exchange.
Definition of pulse, systolic, diastolic, and pulse pressures
Pulse is the pressure wave from heartbeats; systolic pressure is peak arterial pressure; diastolic pressure is minimum arterial pressure; pulse pressure is the difference between systolic and diastolic.
Definition and types of shock
Shock is inadequate cardiac output causing poor tissue perfusion; types include hypovolemic, cardiogenic, distributive, and obstructive shock.
Systemic circulation and its importance
Systemic circulation carries oxygenated blood from the heart to body tissues and returns deoxygenated blood to the heart.
Four principal divisions of the aorta
Ascending aorta, aortic arch, thoracic aorta, and abdominal aorta.
Primary arterial branches of the ascending aorta
The two primary branches are the left and right coronary arteries supplying the heart.
Three principal arteries branching from the aortic arch
Brachiocephalic trunk, left common carotid artery, and left subclavian artery.
Visceral and parietal branches of the thoracic aorta
Visceral branches supply organs; parietal branches supply body wall structures.
Three systemic veins returning deoxygenated blood to the heart
Superior vena cava, inferior vena cava, and coronary sinus.
Components of the lymphatic system
Lymph, lymphatic vessels, lymph nodes, tonsils, spleen, and thymus gland.
Functions of the lymphatic system
Returns interstitial fluid to blood, absorbs fats, and provides immune defense.
Difference between innate and adaptive immunity
Innate immunity is nonspecific and immediate; adaptive immunity is specific and involves memory.
Role of T cells and B cells in adaptive immunity
T cells mediate cell-mediated immunity; B cells produce antibodies for antibody-mediated immunity.
Steps in pulmonary ventilation
Inhalation involves diaphragm contraction and thoracic expansion; exhalation involves relaxation and thoracic recoil.
Differences among tidal volume, inspiratory reserve volume, expiratory reserve volume, and residual volume
Tidal volume is normal breath volume; inspiratory reserve is extra air inhaled; expiratory reserve is extra air exhaled; residual volume is air remaining after forced exhalation.
Phases of digestion
Cephalic phase (prepares mouth and stomach), gastric phase (stomach digestion), and intestinal phase (digestion and absorption in intestines).
Three stages of urine formation
Glomerular filtration, tubular reabsorption, and tubular secretion.
Fluid compartments of the body
Intracellular fluid (inside cells), extracellular fluid (outside cells), including plasma and interstitial fluid.
Functions of sodium, chloride, potassium, bicarbonate, calcium, phosphate, and magnesium ions
These electrolytes regulate fluid balance, nerve and muscle function, pH, and bone structure.
Major events of prenatal development
Fertilization, cleavage, blastocyst formation, implantation, embryonic period, and fetal growth.