Skip to main content
Back

Anatomy & Physiology: Cardiovascular System Exam Prep

Control buttons has been changed to "navigation" mode.
1/30
  • Define stroke volume and cardiac output.

    Stroke volume is the amount of blood ejected by the left ventricle per beat. Cardiac output is the volume of blood the heart pumps per minute, calculated as stroke volume multiplied by heart rate.

  • What are the three main factors affecting stroke volume?

    The three factors are preload (ventricular filling), contractility (strength of contraction), and afterload (resistance to ejection). Increasing preload or contractility increases stroke volume; increasing afterload decreases it.

  • How does a beta blocker work on the heart?

    Beta blockers block beta-1 adrenergic receptors, reducing heart rate and contractility. This lowers cardiac output and oxygen demand. Generic examples include propranolol. They help performance anxiety by reducing sympathetic effects.

  • Define congestive heart failure (CHF).

    CHF is a condition where the heart cannot pump blood effectively, leading to fluid buildup. It can be left-sided (pulmonary congestion) or right-sided (systemic venous congestion).

  • Pathophysiology of left-sided vs right-sided heart failure.

    Left-sided failure causes pulmonary edema and dyspnea due to backup in lungs. Right-sided failure causes peripheral edema and jugular venous distension from systemic venous backup.

  • Causes of left-sided and right-sided heart failure.

    Left-sided causes include ischemic heart disease and hypertension. Right-sided failure often results from left-sided failure or pulmonary diseases like COPD.

  • List four treatments for congestive heart failure and their effects.

    Treatments include diuretics (reduce fluid overload), ACE inhibitors (reduce afterload), beta blockers (reduce heart rate), and digitalis (increase contractility). Therapy varies by dominant side.

  • How does diagnostic work-up distinguish MI from non-ischemic chest pain?

    MI diagnosis uses ECG changes (ST elevation, Q waves) and biomarkers like troponin. Non-ischemic pain lacks these specific changes.

  • Why is atrial repolarization not visible on a standard ECG?

    Atrial repolarization is obscured because it occurs during ventricular depolarization, which produces a larger QRS complex that masks it.

  • Describe the development of atherosclerotic plaques.

    Starts with endothelial injury, followed by lipid accumulation, inflammation, foam cell formation, and fibrous cap development. Plaque stability affects risk of rupture and thrombosis.

  • What is cardiac tamponade and its hemodynamic effect?

    Cardiac tamponade is fluid accumulation in the pericardium that compresses the heart, impairing filling and reducing cardiac output.

  • Key clinical signs of cardiac tamponade.

    Signs include hypotension, jugular venous distension, and muffled heart sounds (Beck's triad).

  • Why is urgent pericardiocentesis needed in tamponade?

    To remove fluid and relieve pressure, restoring cardiac filling and output to prevent cardiovascular collapse.

  • What causes pericarditis and its clinical clues?

    Pericarditis is inflammation of the pericardium, causing chest pain and a pericardial friction rub. ECG may show diffuse ST elevation.

  • How do ectopic pacemakers disrupt heart rhythm?

    They arise from abnormal automaticity or triggered activity, causing premature beats or arrhythmias when normal pacemaker control is lost.

  • Causes and consequences of atrial fibrillation.

    Caused by atrial remodeling or triggers; leads to irregular ventricular response and reduced cardiac efficiency, increasing stroke risk.

  • Difference between rate and rhythm control in atrial fibrillation.

    Rate control manages ventricular rate without restoring sinus rhythm; rhythm control aims to restore and maintain normal rhythm.

  • How does atrial flutter differ from atrial fibrillation on ECG?

    Atrial flutter shows regular sawtooth waves from a reentrant circuit; atrial fibrillation shows irregular, chaotic atrial activity.

  • Why does ventricular fibrillation cause immediate collapse?

    It causes uncoordinated ventricular contractions, stopping effective cardiac output and leading to loss of consciousness.

  • Life-saving intervention sequence for ventricular fibrillation.

    Immediate defibrillation followed by CPR restores coordinated contractions and cardiac output.

  • Risk factors and pathogenesis of infective endocarditis.

    Risk factors include valve disease and IV drug use. Vegetations form from bacterial colonization and platelet-fibrin deposits on valves.

  • Principles guiding antibiotic choice in infective endocarditis.

    Antibiotics target causative organisms, given for prolonged duration to eradicate bacteria in vegetations.

  • How does valve stenosis differ from regurgitation?

    Stenosis narrows valve opening, increasing pressure load. Regurgitation causes backward flow, increasing volume load.

  • Effect of stenosis and regurgitation on chamber remodeling.

    Stenosis causes concentric hypertrophy; regurgitation causes eccentric hypertrophy due to volume overload.

  • How does mitral stenosis affect murmurs and symptoms?

    Mitral stenosis causes a diastolic murmur and symptoms like dyspnea from pulmonary congestion.

  • How does mitral regurgitation affect murmurs and symptoms?

    Mitral regurgitation causes a holosystolic murmur and symptoms of fatigue and pulmonary edema.

  • How does aortic stenosis affect murmurs and symptoms?

    Aortic stenosis causes a systolic ejection murmur and symptoms like syncope and angina.

  • How does aortic regurgitation affect murmurs and symptoms?

    Aortic regurgitation causes a diastolic murmur and symptoms of dyspnea and fatigue.

  • How does tricuspid stenosis affect murmurs and symptoms?

    Tricuspid stenosis causes a diastolic murmur and symptoms of systemic venous congestion.

  • How does tricuspid regurgitation affect murmurs and symptoms?

    Tricuspid regurgitation causes a holosystolic murmur and signs of right heart failure.