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Anatomy & Physiology: Cell Structure and Function
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What are the fundamental units of life?
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What are the fundamental units of life?
Cells are the fundamental units of life, carrying out all functions necessary for life.
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What are the fundamental units of life?
Cells are the fundamental units of life, carrying out all functions necessary for life.
What are the common characteristics of living organisms?
Cellular composition
,
metabolism
(anabolism and catabolism),
growth
,
excretion
,
responsiveness
,
movement
, and
reproduction
.
What are the two main types of cells?
Prokaryotic
cells (no nucleus) and
eukaryotic
cells (with nucleus).
Define anabolism and catabolism.
Anabolism
builds molecules and stores energy;
catabolism
breaks down molecules and releases energy.
What is an oxidation-reduction (redox) reaction?
A chemical reaction where electrons transfer between substances, changing their oxidation states.
Explain oxidation and reduction in redox reactions.
Oxidation
is loss of electrons;
reduction
is gain of electrons.
What are oxidizing and reducing agents?
An
oxidizing agent
gains electrons and causes oxidation; a
reducing agent
loses electrons and causes reduction.
What are the four basic components of most animal cells?
Plasma membrane
,
cytoplasm
(cytosol and organelles),
cytoskeleton
, and
nucleus
.
What is the function of the plasma membrane?
It isolates the cell, provides structural support, communicates with other cells, regulates transport, and identifies the cell.
What is the difference between cytosol and cytoplasm?
Cytosol
is the fluid inside the cell;
cytoplasm
includes cytosol plus organelles and cytoskeleton.
Describe the phospholipid bilayer structure.
A double layer with
hydrophilic polar heads
facing water and
hydrophobic nonpolar tails
facing inward, forming a barrier.
What is the Fluid Mosaic Model of the plasma membrane?
A model describing the membrane as a fluid combination of phospholipids, proteins, cholesterol, and carbohydrates forming a mosaic.
What are integral and peripheral membrane proteins?
Integral proteins
span the membrane;
peripheral proteins
are attached to one side of the membrane.
Name the main functions of membrane proteins.
They act as
channels
,
carriers
,
receptors
,
enzymes
,
structural supports
, and
linkers
.
What is selective permeability of the plasma membrane?
The membrane allows some substances to pass while restricting others, based on size, charge, and solubility.
Define passive transport and give examples.
Movement of substances
down their concentration gradient
without energy, including diffusion, facilitated diffusion, and osmosis.
What is osmosis?
The passive movement of water across a selectively permeable membrane from low to high solute concentration.
Explain tonicity and its types.
Isotonic
: equal solute concentration;
hypertonic
: higher solute outside, cell shrinks;
hypotonic
: lower solute outside, cell swells.
What is active transport?
Movement of substances
against their concentration gradient
using energy (ATP) and carrier proteins called pumps.
Describe the sodium-potassium pump.
It moves 3 Na+ out and 2 K+ into the cell using 1 ATP, maintaining membrane potential essential for nerve and muscle function.
What are vesicular transport processes?
Active transport using vesicles, including
endocytosis
(into cell) and
exocytosis
(out of cell).
What is receptor-mediated endocytosis?
A selective form of endocytosis where ligands bind to specific receptors to form vesicles with high concentrations of substances.
What are membrane-bound organelles?
Organelles enclosed by phospholipid bilayers, such as mitochondria, peroxisomes, endoplasmic reticulum, Golgi apparatus, and lysosomes.
What is the function of mitochondria?
Produce most of the cell's ATP through oxidative catabolism; contain their own DNA and enzymes.
What do peroxisomes do?
Use oxygen to oxidize toxic substances, break down fatty acids, and synthesize certain phospholipids.
What is the role of ribosomes?
Sites of protein synthesis; found free in cytosol or bound to rough ER.
What is the endomembrane system?
A group of organelles (ER, Golgi, lysosomes, plasma membrane) that synthesize, modify, and transport cellular substances.
What is the cytoskeleton and its functions?
A network of protein filaments that maintain cell shape, support membranes and organelles, and enable movement.
Name the three types of cytoskeletal filaments.
Actin filaments
(microfilaments),
intermediate filaments
, and
microtubules
.
What is the nucleus and its main components?
The control center containing DNA, surrounded by the nuclear envelope, with nucleoplasm and nucleolus for RNA synthesis.
What is chromatin and how does it relate to chromosomes?
Chromatin is DNA and proteins in a loose form; it condenses into chromosomes during cell division.
What is protein synthesis?
The process of making proteins from DNA via transcription (DNA to mRNA) and translation (mRNA to protein).
What are the three types of RNA involved in protein synthesis?
mRNA
carries the code,
tRNA
delivers amino acids, and
rRNA
forms the ribosome structure.
What is the cell cycle?
An ordered series of phases (interphase and mitosis) through which a cell grows and divides.
What are the main phases of interphase?
G1
(growth),
S
(DNA synthesis), and
G2
(preparation for mitosis).
What happens during mitosis?
Division of genetic material into two identical sets through prophase, metaphase, anaphase, and telophase.
What are cell cycle checkpoints?
Control points that regulate progression through the cell cycle to ensure proper division.
What is anchorage dependence and density-dependent inhibition?
Mechanisms that regulate cell division by requiring attachment to a surface and stopping division when cells contact each other.
How do cancer cells differ in cell cycle control?
They lack anchorage dependence and density-dependent inhibition, leading to uncontrolled division and tumor formation.