Skip to main content
Back

Anatomy & Physiology Exam 3 Review: Muscle Tissue and Skeletal Muscles

Control buttons has been changed to "navigation" mode.
1/27
  • What are the three muscle types and their key differences?

    The three muscle types are skeletal (voluntary, striated, multinucleated), cardiac (involuntary, striated, branched, with intercalated discs), and smooth (involuntary, non-striated, spindle-shaped cells).

  • What are the four functional characteristics of muscle tissue?

    Excitability, contractility, extensibility, and elasticity.

  • What is a sarcomere?

    The sarcomere is the basic contractile unit of a muscle fiber, composed of overlapping thick (myosin) and thin (actin) filaments between two Z discs.

  • What is the Sliding Filament Model?

    It explains muscle contraction as the thin actin filaments sliding past thick myosin filaments, shortening the sarcomere without changing filament length.

  • What is the role of the sarcoplasmic reticulum (SR) and T tubules in muscle contraction?

    The SR stores calcium ions and releases them to trigger contraction; T tubules transmit action potentials deep into the muscle fiber to stimulate the SR.

  • What is a motor unit?

    A motor unit consists of a single motor neuron and all the muscle fibers it innervates, coordinating contraction.

  • What is the neuromuscular junction?

    The neuromuscular junction is the synapse where a motor neuron communicates with a muscle fiber to initiate contraction.

  • What is acetylcholine (ACh) and its function?

    ACh is a neurotransmitter released at the neuromuscular junction that binds to receptors on the muscle fiber, triggering an action potential.

  • What is an action potential in muscle fibers?

    An action potential is an electrical signal generated by depolarization of the sarcolemma, leading to muscle contraction.

  • What is depolarization and repolarization in muscle cells?

    Depolarization is the influx of Na+ ions making the membrane potential more positive; repolarization restores the resting negative membrane potential by K+ efflux.

  • What is excitation-contraction coupling?

    It is the process where an action potential triggers calcium release from the SR, enabling the sliding filament mechanism and muscle contraction.

  • How does calcium regulate muscle contraction?

    Calcium binds to troponin, causing tropomyosin to move and expose binding sites on actin for myosin, allowing contraction.

  • What are concentric and eccentric muscle contractions?

    Concentric contractions shorten the muscle (lifting), while eccentric contractions lengthen the muscle under tension (lowering).

  • What is a muscle twitch?

    A muscle twitch is a single, brief contraction and relaxation cycle in a muscle fiber following a stimulus.

  • What are graded muscle responses?

    Variations in muscle contraction strength due to changes in stimulus frequency (e.g., tetanus) or stimulus strength (recruitment).

  • What are the three pathways for ATP generation in muscles?

    Direct phosphorylation (creatine phosphate), anaerobic glycolysis, and aerobic respiration, used depending on activity duration and intensity.

  • How do muscle fibers contribute to thermoregulation?

    Muscle contractions produce heat as a byproduct, helping maintain body temperature.

  • How does smooth muscle contraction differ from skeletal muscle?

    Smooth muscle uses calmodulin instead of troponin, contracts slower, and can sustain contractions longer with less energy.

  • What is a gap junction in muscle tissue?

    Gap junctions are channels that allow electrical signals to pass directly between cardiac or smooth muscle cells for coordinated contraction.

  • What is muscle tone?

    Muscle tone is the continuous, passive partial contraction of muscles to maintain posture and readiness.

  • What is sarcopenia?

    Sarcopenia is the age-related loss of muscle mass and strength.

  • What is the function of the diaphragm in respiration?

    The diaphragm is the primary muscle of inspiration, contracting to increase thoracic volume and draw air into the lungs.

  • What are the insertion and origin of a muscle?

    Origin is the fixed attachment point; insertion is the movable attachment where force is applied.

  • How are muscles named?

    Muscles are named based on location, shape, size, direction of fibers, number of origins, or action (e.g., biceps = two heads).

  • What is a fascicle?

    A fascicle is a bundle of muscle fibers surrounded by connective tissue.

  • What are varicosities in smooth muscle?

    Varicosities are swellings along autonomic nerve fibers that release neurotransmitters to smooth muscle cells.

  • What is the stress-relaxation response in smooth muscle?

    It is the ability of smooth muscle to stretch and then relax to accommodate volume changes without contracting.