What percentage of the human body mass is water and why is it important?
Water makes up 60-80% of human body mass and acts as the body's universal solvent because it dissolves many solutes.
What type of molecule is water and how does it dissolve solutes?
Water is a polar covalent molecule with oxygen partially negative and hydrogen partially positive, allowing it to dissolve polar and ionic solutes.
Define acids and bases in terms of hydrogen ions (H+).
Acids are hydrogen ion donors that increase H+ concentration; Bases are hydrogen ion acceptors that decrease H+ concentration.
What does the pH scale represent and what are the ranges for acidic, neutral, and basic solutions?
pH represents H+ concentration on a scale from 0-14; pH 7 is neutral, pH < 7 is acidic, and pH > 7 is basic (alkaline).
What is a buffer and what is the major buffer system in the human body?
A buffer resists pH changes; the major buffer in the body is the bicarbonate (HCO3-) system.
What are salts and electrolytes in the body?
Salts are ionic compounds that dissociate into cations and anions called electrolytes, which conduct electrical current.
What are the four major types of organic compounds in the body?
The four major organic compounds are carbohydrates, lipids, proteins, and nucleic acids.
What is the monomer of carbohydrates and their primary function?
Monosaccharides are carbohydrate monomers; carbohydrates primarily function as energy sources.
What is glycogen and where is it stored?
Glycogen is a polysaccharide storage polymer of glucose, stored mainly in skeletal muscle and liver cells.
Describe saturated, monounsaturated, and polyunsaturated fatty acids.
Saturated fatty acids have no double bonds; monounsaturated have one double bond; polyunsaturated have two or more double bonds.
What is a triglyceride composed of?
A triglyceride consists of three fatty acids linked to a glycerol molecule.
What is the structure and function of phospholipids in the cell membrane?
Phospholipids have a polar phosphate head and two nonpolar fatty acid tails, vital for the plasma membrane structure.
What is cholesterol's role in the body?
Cholesterol is a steroid that forms the basis of all other steroids and is important for cell membrane fluidity and as a precursor for steroid hormones.
What are amino acids and polypeptides?
Amino acids are protein monomers; polypeptides are chains of amino acids forming proteins.
Nucleic acids (DNA and RNA) are polymers made of nucleotides as monomers.
What bases are found in DNA and how do they pair?
DNA bases: Adenine (A), Thymine (T), Cytosine (C), Guanine (G). A pairs with T; G pairs with C.
How does RNA differ from DNA?
RNA is single-stranded, contains ribose sugar, and uses uracil (U) instead of thymine (T).
What is ATP and its role in the body?
ATP (adenosine triphosphate) is the main energy source for cellular processes.
Describe the structure of the plasma membrane.
The plasma membrane is a phospholipid bilayer with hydrophilic phosphate heads facing outward and hydrophobic fatty acid tails facing inward.
What are the main functions of membrane proteins?
Membrane proteins function as channels, carriers, receptors, enzymes, anchors, and facilitate cell adhesion.
What is selective permeability of the plasma membrane?
Selective permeability allows certain molecules to cross while blocking others, enabling controlled transport.
Differentiate between passive and active transport.
Passive transport requires no energy and moves substances down their concentration gradient; active transport requires energy to move substances against their gradient.
What are the types of passive transport?
Diffusion, facilitated diffusion, osmosis, and filtration.
How does facilitated diffusion work?
Facilitated diffusion uses membrane proteins (channels or carriers) to move charged or polar solutes down their concentration gradient.
Describe the sodium-potassium pump function.
The pump uses ATP to move 3 Na+ out and 2 K+ into the cell, maintaining concentration gradients essential for membrane potential.
What is membrane potential?
Membrane potential is the electrical potential difference across the plasma membrane, with the inside of the cell more negative at rest.
What is secondary active transport?
Secondary active transport uses energy stored in concentration gradients of one substance to drive transport of another against its gradient.
What are vesicles and their role in active transport?
Vesicles are small sacs that transport large molecules or particles via endocytosis or exocytosis, requiring ATP.
Differentiate between phagocytosis and pinocytosis.
Phagocytosis is 'cell eating' of large particles; pinocytosis is 'cell drinking' of fluid droplets.
What is exocytosis?
Exocytosis is the process of vesicles fusing with the plasma membrane to release contents outside the cell.