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Anatomy & Physiology: Muscle and Joint Fundamentals

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  • Muscle tension

    Muscle tension is the force produced when muscle fibers contract and depends on how many fibers are stimulated.

  • Motor unit

    A motor unit consists of one motor neuron and all the muscle fibers it controls, allowing coordinated muscle contraction.

  • Recruitment

    Recruitment is the gradual increase in muscle tension by activating more motor units, starting with small units and progressing to larger ones.

  • Muscle tone

    Muscle tone is the continuous, low-level tension in resting muscles that helps maintain posture and stabilize joints.

  • Isotonic contraction

    Isotonic contractions change muscle length while producing tension; includes concentric (muscle shortens) and eccentric (muscle lengthens) types.

  • Concentric contraction

    A concentric contraction occurs when muscle tension exceeds the load and the muscle shortens, like lifting a dumbbell.

  • Eccentric contraction

    An eccentric contraction occurs when muscle tension is less than the load and the muscle lengthens while controlling movement, like lowering a dumbbell.

  • Isometric contraction

    Isometric contractions produce tension without changing muscle length, such as holding a weight steady without movement.

  • ATP in muscle contraction

    ATP provides the direct energy for muscle contraction and must be continuously regenerated during activity.

  • Creatine phosphate

    Creatine phosphate stores high-energy phosphate groups to quickly regenerate ATP during short, intense muscle activity.

  • Glycolysis

    Glycolysis is an anaerobic process breaking down glucose into pyruvate, producing 2 ATP quickly but less efficiently than aerobic metabolism.

  • Aerobic metabolism

    Aerobic metabolism uses oxygen in mitochondria to produce ATP efficiently, supporting prolonged, moderate muscle activity.

  • Muscle hypertrophy

    Hypertrophy is the increase in muscle size due to repeated high-tension stimulation, increasing fiber diameter and contractile proteins.

  • Muscle atrophy

    Atrophy is the decrease in muscle size, tone, and strength caused by disuse or injury.

  • Delayed-Onset Muscle Soreness (DOMS)

    DOMS is muscle soreness starting hours after exercise, often from eccentric contractions, caused by microtears and inflammation.

  • Cardiac muscle intercalated discs

    Intercalated discs connect cardiac muscle cells with gap junctions for electrical signals and desmosomes for mechanical strength.

  • Smooth muscle plasticity

    Plasticity is smooth muscle's ability to adjust length while maintaining contractile ability, important for organs like the bladder.

  • Excitation–contraction coupling in skeletal muscle

    Electrical signals trigger the sarcoplasmic reticulum to release calcium, which binds troponin, moving tropomyosin and allowing myosin to bind actin.

  • Length–tension relationship

    The length–tension relationship describes how muscle fibers produce maximum tension at an optimal resting length due to optimal actin-myosin overlap.

  • Tetanus (muscle physiology)

    Tetanus is a sustained muscle contraction caused by rapid, repeated stimulation, with complete tetanus showing no relaxation between stimuli.

  • Sliding-filament theory

    The sliding-filament theory explains muscle contraction as thin actin filaments sliding past thick myosin filaments, shortening sarcomeres.

  • Types of synovial joints

    Synovial joints include plane (gliding), hinge, pivot, condylar, saddle, and ball-and-socket, each allowing specific movement types.

  • Flexion vs. extension

    Flexion decreases joint angle; extension increases joint angle, returning a limb toward anatomical position.

  • Abduction vs. adduction

    Abduction moves a body part away from the midline; adduction moves it toward the midline.

  • Pronation vs. supination

    Pronation rotates the forearm so the palm faces backward; supination rotates it so the palm faces forward.

  • ACL vs. PCL function

    The ACL prevents anterior tibial displacement; the PCL prevents posterior tibial displacement in the knee joint.

  • Osteoarthritis vs. rheumatoid arthritis

    Osteoarthritis is degenerative cartilage wear; rheumatoid arthritis is an autoimmune inflammatory joint disease.

  • Muscle fatigue causes

    Muscle fatigue results from energy depletion, muscle damage, and pH changes interfering with contraction processes.