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Anatomy & Physiology: Skeletal System Basics

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  • Functions of the skeletal system

    Support, protection, movement, mineral storage, blood cell production, and energy storage.

  • Five types of bone classification

    Long, short, flat, irregular, and sesamoid bones.

  • Epiphysis

    The rounded end of a long bone, usually covered with articular cartilage.

  • Diaphysis

    The shaft or central part of a long bone.

  • Spongy bone

    Light, porous bone found mainly in the epiphysis; contains trabeculae and bone marrow.

  • Compact bone

    Dense bone forming the outer layer of bones, composed of osteons.

  • Articular cartilage

    Hyaline cartilage covering the epiphysis to reduce friction in joints.

  • Periosteum

    A dense connective tissue membrane covering the outer surface of bones except at joints.

  • Perforating fibers

    Collagen fibers that connect the periosteum to the bone matrix.

  • Medullary cavity

    The hollow central cavity inside the diaphysis containing bone marrow.

  • Endosteum

    A thin membrane lining the medullary cavity and inner surfaces of bone.

  • Bone marrow

    Soft tissue inside bones; red marrow produces blood cells, yellow marrow stores fat.

  • Osteons

    Structural units of compact bone, consisting of concentric lamellae around a central canal.

  • Lamellae

    Concentric rings of mineralized matrix in osteons.

  • Central canal

    Channel in the center of an osteon containing blood vessels and nerves.

  • Interstitial lamellae

    Remnants of old osteons found between new osteons in compact bone.

  • Circumferential lamellae

    Layers of bone matrix that run around the entire circumference of the bone.

  • Perforating canals

    Channels that connect central canals of osteons to each other and to the periosteum.

  • Trabeculae

    Thin columns of spongy bone that provide structural support and house marrow.

  • Extracellular matrix (ECM) of bone tissue

    Composed of organic components like collagen and inorganic minerals like hydroxyapatite for strength.

  • Osteoblasts

    Bone-forming cells that secrete matrix and initiate mineralization.

  • Osteocytes

    Mature bone cells embedded in the matrix that maintain bone tissue.

  • Osteoclasts

    Large cells that resorb or break down bone matrix during remodeling.

  • Bone deposition

    The process of adding new bone matrix by osteoblasts.

  • Canaliculi

    Small channels connecting osteocytes, allowing nutrient and waste exchange.

  • Osteoporosis

    A condition characterized by decreased bone density and increased fracture risk.

  • Intramembranous ossification

    Bone formation directly from mesenchymal tissue, mainly forming flat bones.

  • Endochondral ossification

    Bone formation by replacing hyaline cartilage, typical in long bones.

  • Mesenchymal cells

    Stem cells that differentiate into osteoblasts during bone formation.

  • Fontanels

    Soft spots on an infant's skull where intramembranous ossification is incomplete.

  • Perichondrium

    Dense connective tissue surrounding cartilage, involved in appositional growth.

  • Epiphyseal plate

    Cartilage plate in long bones where lengthwise growth occurs during childhood.

  • Appositional growth

    Growth in bone thickness by adding new layers on the surface.