Ch. 3 Review
Terms in this set (89)
Cells are...
the smallest living unit that carry out physiological functions in order to maintain homeostasis.
Plasma Membrane is ...
outer boundary of a cell.
Functions of a Plasma Membrane...
regulates: passage of substances
separates: fluid on the inside/outside
physical separation:
sensitivity: receptors allow communication
support: anchors cells together.
Cells have a Phospholipid bilayer that contains ...
hydrophilic heads
hydrophobic tails
Hydrophilic Heads in a phospholipid bilayer...
heads with POLAR covalent bonds that ATRACT water. (in contact with ECF, ICF)
Hydrophobic Tails in a phospholipid bilayer...
have NONPOLAR covalent bonds which repel ions/water.
cholesterol in the plasma membrane...
a type of lipid that stiffens the plasma membrane making it less of a "fluid" and less permeable.
Proteins associated with the plasma membrane...
integral proteins -> embedded within cell membrane
transmembrane -> integral proteins that span entire width of membrane
peripheral proteins -> bound to inner or outer surface of membrane
Cytoplasm...
all material between plasma membrane and membrane of the nucleus.
Three major parts of the cytoplasm are...
Cytosol (ICF)
organelles
Inclusions
Cytosol (major part of the cytoplasm) is...
mixture of water + dissolved nutrients, ions, proteins, waste (JELLY-LIKE SUBSTANCE)
Organelles of the Cytoplasm are ...
internal structures with a specific function. ("LITTLE ORGANS")
Inclusions in the Cytoplasm are...
insoluble materials within cells (glycogen granules, skeletal cells)
non membranous organelles in the cytoplasm...
not completely enclosed by membranes -> in direct contact with cytosol.
membranous organelles in the cytoplasm...
are completely enclosed by membrane -> isolated from cytosol.
Cytoskeleton of a cell...
internal framework of proteins in cytoplasm.
The three types of cytoskeletal fibers are...
microfilaments
intermediate filaments
microtubules
Functions of Microfilaments (smallest) in the cytoskeleton...
mechanical strength
attaching plasma membrane -> cytoplasm
protein interactions that determine -> consistency of cytosol (jelly->)
Functions of Intermediate Filaments (medium) in the cytoskeleton...
strengthening cell + maintain shape
stabilizing organelles
Functions of Microtubules (Largest) in the cytoskeleton...
radiate outward from centrosome
cell movement
forming spindle apparatus during cell division
Centrosome...
A region of the cytoplasm that organizes microtubules.
Centrioles located in the centrosome ...
a PAIR of cylindrical structures that form spindle apparatus during cell division.
Ribosomes...
organelles that make proteins and are made of two subunits of differing size + rRNA
Free Ribosomes...
scattered throughout cytoplasm that makes protein that goes straight into the fluid.
Fixed Ribosomes...
are attached to the rough endoplasmic reticulum.
Endoplasmic Reticulum...
network of intracellular membranes that are continuous with nuclear envelope.
Functions of Endoplasmic Reticulum (ER) are ...
makes proteins, carbohydrates, lipids
storage
transport
detoxification
Functions of the Smooth endoplasmic Reticulum (SER)...
lacks fixed ribosomes
makes phospholipids/cholesterol
makes steroid hormones in reproductive organs
making + storage of triglycerides in liver and fat
making + storage of glycogen -> skeletal muscle and liver cels
Functions of the rough endoplasmic Reticulum (RER)...
synthesis of proteins by fixed ribosomes
chemical modification of newly made proteins in the RER
packages modified proteins -> into transport vesicles
the place where proteins fold
Golgi Apparatus...
organelle composed of flattened membranous discs (cisternae) that modifies and packages secretions. Proteins arrive here from the RER
Functions of the Golgi Apparatus include...
Modify and package secretions.
Lysosomes are ...
vesicles produced by Golgi apparatus that contain digestive enzymes.
membrane eclosed isolated environment (compartmentalization)
enzymatic reaction occurring within lysosomes -> toxic chemicals
Functions of Lysosomes...
use hydrolysis reaction to break polymers -> monomers -> new organelles
recycling damaged organelles
killing bacteria
autolysis: self-destruction of damaged cells.
enzymatic reactions...
generates toxic chemicals that can end the cell.
compartmentalization of lysosomes...
isolated environed (membrane enclosed) in order to allow enzymatic reactions and autolysis to occur.
Mitochondria in a cell tells you...
the energy demands of a cell, as well as what the cell is doing. (where ATP is made)
Nucleus Functions...
stores DNA
controls which, when, and how many PROTEINS are made.
determines cell structure and function.
Has two bilayers
Nuclear envelope...
double membrane surrounding the nucleus -> connected to the RER
nuclear pore...
openings in the nuclear envelope that allow communication between the nucleus and cytoplasm.
Nuclear Pore Complex (NPC)...
proteins in the nuclear pore that control what goes in and out of the nucleus.
Nucleolus...
organelles INSIDE nucleus that makes ribosomes.
nucleosomes...
DNA coiled around histones (circular proteins)
Cells that ARE NOT going to divide...
have LOOSLEY coiled DNA around histone -> CHROMATIN
Cells that WILL divide...
have TIGHTLY coiled DNA around histone -> CHROMOSOMES
Gene...
DNA nucleotide sequence that codes for amino acid sequence of one protein.
central dogma of molecular biology says that...
DNA sequence is TRANSCRIBED into mRNA, THEN mRNA sequence is TRANSLATED into protein amino acid sequence.
Transcription of DNA...
MAKES RNA from DNA template. DNA is copied to mRNA since mRNA can leaved nucleus using uracil (U).
DNA: A -> RNA: U
DNA: T-> RNA: A
DNA: G-> RNA: C
DNA: C-> RNA: G
Translation...
making of a polypeptide by translating info from mRNA -> amino acid of a polypeptide. (tRNA anticodons complementary to mRNA codons)
Codons...
3 bases of sequence that translates into amino acid.
DNA: A T A T G G C T A T G C
Transcribed->
mRNA: U A U A C C G A U A C G
RNA processing...
turns immature RNA into a protein by removing introns -> Mature RNA leaves nucleus -> TRANSLATION outside of the nucleus.
Diffusion...
movement of substance from a higher concentration area -> lower concentration. (eliminates gradient)
Concentration gradient...
difference between high/low concentration of substances.
Diffusion throughout the plasma membrane uses...
simple diffusion
channel-mediated diffusion.
Simple Diffusion...
no channel needed, lipid soluble compounds pass through membrane.
channel-mediated diffusion...
water-soluble compounds pass through
Osmosis...
diffusion of water in response to different solute (the thing GETTING dissolved) concentration.
Equilibrium...
concentration is equal on both sides of the membrane.
Tonicity...
describes the shape of cell as a result of concentration of solutes.
Isotonic fluid...
means the solute concentration of ICF/ECF is equal -> no Osmosis
hypotonic amount of fluid...
solute concentration of ICF is higher than ECF -> causing water to enter membrane -> hemolysis (cell burst)
hypertonic...
solute concentration of ICF is lower than ECF water exits
carrier-mediated transport...
movement of a substance across cell membrane using carrier protein (specific to ONE substance).
carrier proteins...
connects ions and carry's them across membrane (specific to ONE substance)
symporters...
carrier proteins that carry two substances in the same direction at the same time.
antiporters...
carries substances in the opposite direction at the same time. (exchange pump)
Sodium-Potassium exchange pump...
exchanges sodium inside cell for potassium outside of the cell.
Cell Division divides a cell into 2 daughter cels through...
mitosis and cytokinesis
Mitosis is the division of...
Body cells.
Meiosis is the division of...
sex cells
Interphase is the ___ phase of the CELL LIFE CYCLE...
FIRST
True or False: Interphase is where body cells spend MOST of their life.
TRUE
The 3 MAIN phases where the cell PREPARES TO DIVIDE of Interphase are...
G1
S
G2
G0...
when the cell leaves the life cycle and is NOT ACTIVLEY PREPARING FOR DIVISION!
phase G1 of Interphase...
is the time where CELLS GROW
organelles duplicate (enough for TWO cells)
phase S of Interphase...
is when DNA REPLICATION occurs. (one chromosome -> 2 identical daughter cells)
Centromere...
where the two identical daughter cells connect AFTER DNA replication.
FORMED BY KINTOCHORE
phase G2 of the Interphase...
is the making of (microtubular) proteins
preparing for M phase
M PHASE (2nd stage of life cycle) includes...
Mitosis and cytokinesis
Mitosis is the process of division of...
the nucleus.
Cytokinesis is the process of division of...
cytoplasm. (outside of the nucleus)
The Phases of Mitosis (division of the nucleus) are...
Prophase \
Metaphase PMAT
Anaphase /
Telophase
PROPHASE (1st phase of M phase) ...
chromatin condenses -> chromosomes (become visible)
nuclear envelope disintegrates
microtubules form Mitotic Spindle
Kinetochore...
protein structure that FORMS centromere.
give place for spindle to attach too
METAPHASE (2nd phase of M phase) ...
chromatids line up at metaphase plate (the middle)
ANAPHASE (3rd phase of M phase) ...
Chromatid pairs -> SEPERATE
TELOPHASE (final phase of M phase) ...
nucleus ENLARGES
chromosomes GO BACK to chromatin
mitotic spindle breaks down (gets recycled)
Cytokinesis occurs...
at the END of anaphase -> Telophase.
During Cytokinesis what forms?
cleavage furrow.
The Contractile Band squeezes cells into separation during...
Cytokinesis.