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Chapter 6 Bone Tissue Review - Anatomy & Physiology

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  • Types of bones by shape

    Long bones are longer than wide; short bones are cube-shaped; flat bones are thin and flat; irregular bones have complex shapes; sesamoid bones develop within tendons.

  • Difference between intramembranous and endochondral bone

    Intramembranous bone forms directly from mesenchymal tissue; endochondral bone forms by replacing hyaline cartilage.

  • Compact bone vs spongy bone

    Compact bone is dense and forms the outer layer; spongy bone is porous, found inside bones, and contains trabeculae.

  • Periosteum

    A dense connective tissue membrane covering the outer surface of bones, containing osteoblasts for growth and repair.

  • Endosteum

    A thin membrane lining the marrow cavity and inner surfaces of bones, containing osteogenic cells.

  • Epiphysis

    The expanded end of a long bone, usually covered with articular cartilage.

  • Diaphysis

    The shaft or central part of a long bone.

  • Osteocyte

    A mature bone cell that maintains the bone matrix and resides in lacunae.

  • Osteoblast

    A bone-forming cell that secretes osteoid and initiates calcification.

  • Osteoclast

    A large cell that resorbs or breaks down bone matrix during remodeling.

  • Haversian system (osteon)

    The structural unit of compact bone, consisting of concentric lamellae around a central canal containing blood vessels and nerves.

  • Lamellae

    Concentric rings of calcified matrix in compact bone surrounding the central canal.

  • Canaliculi

    Microscopic canals connecting lacunae, allowing osteocytes to communicate and exchange nutrients.

  • Marrow cavity

    The central cavity within the diaphysis that contains bone marrow.

  • Epiphyseal plate

    A hyaline cartilage plate in the metaphysis where bone growth occurs in children and adolescents.

  • Intramembranous ossification steps

    Mesenchymal cells differentiate into osteoblasts, secrete osteoid, which calcifies, forming spongy bone that remodels into compact bone.

  • Endochondral ossification steps

    Hyaline cartilage model forms, cartilage calcifies, chondrocytes die, and bone tissue replaces cartilage from the diaphysis outward.

  • Functions of the skeletal system

    Support, protection, movement, mineral storage, and blood cell production.

  • Bone remodeling homeostasis

    Balance between osteoblast bone formation and osteoclast bone resorption to maintain bone strength and calcium levels.

  • Conditions for normal bone growth

    Requires adequate nutrition, hormones (growth hormone, thyroid hormone), mechanical stress, and vitamin D.

  • Bone fracture repair process

    Hematoma formation, fibrocartilaginous callus formation, bony callus formation, and bone remodeling.

  • Role of parathyroid hormone (PTH) in calcium regulation

    PTH increases blood calcium by stimulating osteoclasts, increasing intestinal absorption, and reducing kidney excretion.

  • Role of calcitonin in calcium regulation

    Calcitonin lowers blood calcium by inhibiting osteoclast activity and promoting calcium deposition in bone.

  • Bone markings: process, tubercle, and trochanter

    Process is a projection; tubercle is a small rounded projection; trochanter is a large, blunt projection.

  • Bone markings: foramen, fissure, and sinus

    Foramen is a hole for blood vessels/nerves; fissure is a narrow slit; sinus is a cavity within a bone.

  • Metaphysis

    The region of a long bone between the diaphysis and epiphysis containing the epiphyseal plate.

  • Spongy bone histology

    Consists of trabeculae with spaces filled by marrow; lacks osteons found in compact bone.

  • Compact bone histology

    Organized into osteons with central canals, lamellae, lacunae, and canaliculi.