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Study Guide: Muscular System 2/4

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  • Fascia

    Fascia is a layer of connective tissue that surrounds muscles, groups of muscles, blood vessels, and nerves, binding them together and providing support.

  • Perimysium

    Perimysium is the connective tissue sheath that surrounds each muscle fascicle (a bundle of muscle fibers).

  • Epimysium

    Epimysium is the dense connective tissue layer that surrounds the entire muscle.

  • Endomysium

    Endomysium is the thin connective tissue layer that surrounds each individual muscle fiber.

  • Muscle compartment

    A muscle compartment is a group of muscles enclosed by fascia, often sharing similar functions and nerve supply.

  • Muscle

    A muscle is an organ composed of muscle tissue, connective tissue, blood vessels, and nerves that produces force and movement.

  • Muscle fascicle

    A muscle fascicle is a bundle of muscle fibers surrounded by perimysium.

  • Muscle fiber

    A muscle fiber is a single muscle cell, multinucleated and surrounded by endomysium.

  • Myofibril

    Myofibrils are long, cylindrical organelles inside muscle fibers composed of repeating sarcomeres, responsible for contraction.

  • Myofilament

    Myofilaments are the protein filaments (actin and myosin) that make up myofibrils and enable muscle contraction.

  • Satellite cell

    Satellite cells are muscle stem cells involved in growth, repair, and regeneration of muscle tissue.

  • Sarcoplasm

    Sarcoplasm is the cytoplasm of a muscle fiber, containing glycogen, mitochondria, and myoglobin.

  • Sarcolemma

    Sarcolemma is the plasma membrane surrounding a muscle fiber, involved in conducting electrical impulses.

  • Sarcomere

    A sarcomere is the functional contractile unit of a myofibril, defined by Z-disks at each end.

  • T-tubule

    T-tubules are invaginations of the sarcolemma that transmit action potentials deep into the muscle fiber.

  • Terminal cistern

    Terminal cisternae are enlarged areas of the sarcoplasmic reticulum that store calcium ions near T-tubules.

  • S.R.

    Sarcoplasmic reticulum (S.R.) is a specialized smooth endoplasmic reticulum that stores and releases calcium ions for muscle contraction.

  • Triad

    A triad consists of a T-tubule flanked by two terminal cisternae of the sarcoplasmic reticulum, coordinating calcium release.

  • Actin

    Actin is the thin filament protein that interacts with myosin during muscle contraction.

  • Myosin

    Myosin is the thick filament protein with heads that bind to actin to generate contraction force.

  • Troponin

    Troponin is a regulatory protein on actin filaments that binds calcium to initiate contraction.

  • Tropomyosin

    Tropomyosin is a regulatory protein that blocks myosin-binding sites on actin when muscle is relaxed.

  • Z-disk

    Z-disks define the boundaries of a sarcomere and anchor thin filaments.

  • M-line

    M-line is the central line of the sarcomere where thick filaments are anchored.

  • Titin

    Titin is a large elastic protein that stabilizes thick filaments and contributes to muscle elasticity.

  • Dystrophin

    Dystrophin is a protein that links the cytoskeleton of muscle fibers to the extracellular matrix, providing structural support.

  • I band

    The I band is the light region of the sarcomere containing only thin filaments.

  • A band

    The A band is the dark region of the sarcomere containing the entire length of thick filaments.

  • H zone

    The H zone is the central part of the A band where only thick filaments are present.

  • Zone of overlap

    The zone of overlap is the region in the sarcomere where thick and thin filaments overlap.

  • Sliding filament theory

    The sliding filament theory explains muscle contraction as thin filaments sliding past thick filaments, shortening the sarcomere.