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Study Guide: Muscular System 3/4

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  • Voltage

    Voltage is the electrical potential difference between two points, representing stored energy that can cause current to flow.

  • Membrane potential

    Membrane potential is the voltage difference across a cell's plasma membrane due to ion distribution.

  • Electricity

    Electricity is the flow of electric charge, often carried by electrons or ions.

  • Leakage channel

    Leakage channels are ion channels that are always open, allowing ions to move down their concentration gradient.

  • Ligand-gated channel

    Ligand-gated channels open or close in response to a specific chemical binding (ligand) to the channel.

  • Voltage-gated channel

    Voltage-gated channels open or close in response to changes in membrane potential.

  • Resting membrane potential

    Resting membrane potential is the stable voltage across the membrane of a resting cell, typically around -70 mV in neurons.

  • Action potential

    Action potential is a rapid, temporary change in membrane potential that propagates along excitable cells.

  • Electrochemical gradient

    Electrochemical gradient is the combined effect of ion concentration and electrical charge differences across a membrane.

  • Depolarization

    Depolarization is the process where the membrane potential becomes less negative (more positive) than the resting potential.

  • Repolarization

    Repolarization is the return of the membrane potential to the resting negative value after depolarization.

  • AP propagation

    Action potential propagation is the movement of the action potential along the membrane of a neuron or muscle fiber.

  • Neuromuscular junction

    Neuromuscular junction is the synapse between a motor neuron and a skeletal muscle fiber.

  • Synaptic bulb

    Synaptic bulb is the swollen end of a motor neuron axon that releases neurotransmitters.

  • Synaptic cleft

    Synaptic cleft is the small gap between the synaptic bulb and the motor end plate.

  • Motor end plate

    Motor end plate is the specialized region of the muscle fiber membrane at the neuromuscular junction.

  • Innervation

    Innervation is the supply of nerves to a specific body part, such as a muscle.

  • Acetylcholine

    Acetylcholine is a neurotransmitter released at the neuromuscular junction to stimulate muscle contraction.

  • Acetylcholinesterase

    Acetylcholinesterase is the enzyme that breaks down acetylcholine in the synaptic cleft to terminate the signal.

  • Excitation

    Excitation is the process of generating an action potential in a muscle fiber in response to a stimulus.

  • End plate potential

    End plate potential is the local depolarization of the motor end plate caused by acetylcholine binding.

  • Excitation-Contraction coupling

    Excitation-contraction coupling is the sequence linking muscle fiber excitation to contraction via calcium release.

  • Contraction cycle

    Contraction cycle is the repeating sequence of events where myosin heads bind, pivot, and release actin to shorten muscle fibers.

  • Rigor mortis

    Rigor mortis is the stiffening of muscles after death due to lack of ATP preventing myosin release from actin.

  • Creatine

    Creatine is a molecule stored in muscle cells used to regenerate ATP during short bursts of activity.

  • Creatine phosphate

    Creatine phosphate is a high-energy compound that donates a phosphate to ADP to quickly regenerate ATP.

  • Creatine kinase

    Creatine kinase is the enzyme that catalyzes the transfer of a phosphate group from creatine phosphate to ADP.