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A patient has a condition that prevents the activation of chymotrypsinogen. What effect would this have on protein digestion?
In the catalytic triad, what role does histidine 57 play in the mechanism of chymotrypsin?
What type of bonds does chymotrypsin cleave in proteins?
A researcher is studying a new enzyme similar to chymotrypsin. What characteristic should they expect this enzyme to have?
Explain how aspartate 102 influences the role of histidine 57 in chymotrypsin's catalytic mechanism.
A mutation in chymotrypsin prevents covalent catalysis. What effect would this have on enzyme activity?
What is the significance of chymotrypsin's preference for aromatic amino acid residues?