What is the primary role of citrate synthase in the citric acid cycle?

Why is the aconitase-catalyzed reaction considered reversible under cellular conditions?

Analyze the reaction catalyzed by isocitrate dehydrogenase. What are the products generated?

Apply your knowledge of citrate synthase's role in the citric acid cycle. What would be the consequence of a mutation that reduces its activity?

Synthesize the role of iron sulfur complexes in aconitase. How do they contribute to its function beyond the citric acid cycle?

How does aconitase's auxiliary function contribute to iron regulation in the body?

Synthesize the information about citrate synthase's role. How does its activity influence the overall citric acid cycle?