What is the primary reason detergents are required to isolate integral membrane proteins from the membrane?

How does the hydrophobic environment within the membrane contribute to the stability of alpha helix structures in integral membrane proteins?

Analyze the folding pattern of proteins in hydrophobic environments and compare it to their folding in polar aqueous environments.

What is the functional role of the hydrophilic interior of beta barrel motifs in porins?

Why are alpha helix structures prevalent in integral membrane proteins?

What is a transmembrane spanning domain typically composed of in integral membrane proteins?

How does the presence of porins in mitochondria and chloroplasts support the endosymbiotic theory?