Biochemistry
What is a ligand in the context of protein-ligand interactions?
Which of the following statements correctly differentiates protein-ligand interactions from enzyme-substrate interactions?
In protein-ligand interactions, what does the association rate constant (ka) represent?
In a drug design scenario, why is it important to consider the ratio of ka/kd for a potential drug candidate?
How do the principles of protein-ligand interactions provide a foundation for understanding signal transduction pathways in cells?
Why is the dissociation rate constant (kd) critical in evaluating the stability of a protein-ligand complex?
If the association rate constant (ka) is 2 x 10^7 M^-1s^-1 and the dissociation rate constant (kd) is 2 x 10^-4 s^-1, what is the ratio ka/kd and what does it indicate?
