Biochemistry
What is the primary effect of uncoupling agents like DNP and FCCP on ATP production?
Why does electron transport continue in the presence of uncoupling agents?
In a scenario where the inner mitochondrial membrane is damaged, what would be the immediate effect on ATP synthesis?
What is the inheritance pattern of mitochondrial genes?
Predict the change in the PO ratio if an uncoupling agent is added to a mitochondrial preparation.
How might mitochondrial gene mutations affect a patient's energy metabolism?
Propose a method to investigate the effect of proton gradient disruption on ATP synthesis in a laboratory setting.