Biochemistry
How do tumor suppressor genes function in the regulation of cell division?
A mutation in a proto oncogene leads to the formation of an oncogene. What is the likely consequence of this mutation?
What is the impact of losing intrinsic GTPase activity in Ras proteins?
Given a signaling defect in Ras proteins, what is a potential outcome in cancer progression?
Evaluate the role of phosphatases as tumor suppressor genes and the impact of their mutations.
What happens to cell growth regulation when tumor suppressor genes are mutated?
How do signal transduction events contribute to the activation of oncogenes and mutated tumor suppressor genes?
