What are the three basic parts of a generalized human cell?
Plasma membrane (flexible outer boundary), cytoplasm (intracellular fluid with organelles), and nucleus (DNA-containing control center).
What is the primary function of mitochondria?
Mitochondria produce most of the cell's energy molecules (ATP) via aerobic cellular respiration.
Describe the structure of mitochondria.
Double membrane organelle; inner membrane has folds called cristae embedded with proteins for respiration; contains its own DNA, RNA, and ribosomes.
What are ribosomes and their two forms?
Nonmembranous organelles for protein synthesis; free ribosomes synthesize soluble proteins in cytosol, membrane-bound ribosomes synthesize proteins for membranes or export.
What are the two types of endoplasmic reticulum (ER) and their functions?
Rough ER has ribosomes; synthesizes proteins for secretion or membranes. Smooth ER lacks ribosomes; involved in lipid metabolism, steroid synthesis, detoxification, glycogen breakdown, and calcium storage.
What is the role of the Golgi apparatus?
Modifies, concentrates, and packages proteins and lipids from rough ER into vesicles for transport or secretion.
What are lysosomes and their functions?
Membranous sacs with digestive enzymes that break down bacteria, viruses, toxins, nonfunctional organelles, glycogen, and release calcium from bone.
What is the cytoskeleton and its three main components?
Network of protein rods providing cell structure and movement; includes microfilaments, intermediate filaments, and microtubules.
What are microfilaments composed of and their function?
Thinnest cytoskeletal elements made of actin; involved in cell motility, shape changes, endocytosis, and exocytosis.
What is the function of intermediate filaments?
Intermediate-sized cytoskeletal fibers that provide tensile strength and resist pulling forces on the cell.
Describe microtubules and their role in the cell.
Largest cytoskeletal elements; hollow tubes of tubulin; determine cell shape and organelle distribution.
What is the centrosome and what does it contain?
Microtubule organizing center near the nucleus; contains a granular matrix and a pair of centrioles.
What are centrioles and their functions?
Barrel-shaped microtubular organelles that organize mitotic spindle during cell division and form bases of cilia and flagella.
What are cilia and their function?
Short, motile cellular extensions that move substances across cell surfaces, e.g., mucus in respiratory tract.
What is a flagellum and which human cell has it?
Longer motile extension that propels the whole cell; only human cell with flagellum is sperm.
What are the three main structures of the nucleus?
Nuclear envelope, nucleoli, and chromatin.
Describe the nuclear envelope.
Double membrane barrier enclosing nucleoplasm; outer membrane continuous with rough ER and studded with ribosomes; contains nuclear pores for substance exchange.
What is the function of nucleoli?
Dark-staining bodies in nucleus involved in ribosomal RNA synthesis and ribosome subunit assembly.
What is chromatin composed of?
30% DNA, 60% histone proteins, and 10% RNA; chromosomes are condensed chromatin for protection during cell division.
What is the cell theory?
Cells are the smallest unit of life; all organisms are made of cells; cells arise only from other cells.