Nuclei are clusters of neuron cell bodies in the CNS; ganglia are clusters in the PNS.
Difference between white matter and grey matter
White matter contains myelinated axons; grey matter contains neuron cell bodies and unmyelinated fibers.
Anatomy and function of the myelin sheath
Myelin sheath is a fatty layer formed by oligodendrocytes in CNS and Schwann cells in PNS; it insulates axons and speeds up action potential conduction.
Resting membrane potential generation
Generated by ion concentration gradients and selective permeability of the membrane, mainly via Na+/K+ pumps and leak channels.
Difference between graded potentials and action potentials
Graded potentials are local, vary in strength, and can summate; action potentials are all-or-none, propagate without decrement.
Absolute vs. relative refractory periods
Absolute: no new AP possible; Relative: AP possible but requires stronger stimulus.
All-or-none phenomenon of action potentials
An AP either occurs fully if threshold is reached or not at all; stimulus strength does not affect AP size.
Two major factors influencing AP conduction velocity
Axon diameter (larger is faster) and myelination (myelinated axons conduct faster).
Difference between continuous and saltatory conduction
Continuous conduction occurs in unmyelinated axons; saltatory conduction jumps between Nodes of Ranvier in myelinated axons.
Excitatory postsynaptic potential (EPSP)
A depolarizing graded potential caused by excitatory synapses opening Na+ channels.
Inhibitory postsynaptic potential (IPSP)
A hyperpolarizing graded potential caused by inhibitory synapses opening K+ or Cl- channels.
Primary brain vesicles during embryonic development
Prosencephalon, Mesencephalon, and Rhombencephalon.
Secondary brain vesicles and adult brain structures
Prosencephalon divides into telencephalon (cerebrum) and diencephalon; Mesencephalon remains; Rhombencephalon divides into metencephalon (pons, cerebellum) and myelencephalon (medulla).
Ventricular system flow of cerebrospinal fluid (CSF)