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Anatomy & Physiology: Histology and Tissue Types

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  • What are the four basic types of human tissue?

    Epithelial, connective, muscle, and nervous tissue.

  • What are the two basic components shared by all tissues?

    Cells and extracellular matrix (ECM).

  • What are the main elements of the extracellular matrix (ECM)?

    Ground substance (gel-like material) and protein fibers (collagen, elastic, reticular).

  • What is the function of collagen fibers in ECM?

    Strongest and most abundant fiber type; tough yet flexible.

  • What is the role of elastic fibers in connective tissue?

    Allow tissue to stretch and recoil.

  • What is the function of reticular fibers?

    Short, branched collagen fibers that stabilize positions of blood vessels and nerves.

  • What is epithelial tissue and its main functions?

    Sheets of cells covering body surfaces or cavities; functions include protection, absorption, filtration, excretion, secretion, and sensory reception.

  • What are the two surfaces of epithelial cells and their characteristics?

    Apical surface exposed to outside or open space; basal surface anchored to connective tissue by basal lamina.

  • Is epithelial tissue vascular or avascular?

    Avascular; obtains nutrients by absorption or diffusion from underlying connective tissue.

  • How is epithelial tissue classified by cell layers?

    Simple (single layer) and stratified (two or more layers).

  • How is epithelial tissue classified by cell shape?

    Squamous (flat), cuboidal (cube-shaped), and columnar (tall, rectangular).

  • Where is simple squamous epithelium found and what is its function?

    Single layer of flat cells; found in alveoli and serous membranes; functions in diffusion and filtration.

  • What is the function of simple cuboidal epithelium and where is it found?

    Secretion and absorption; found in kidney tubules and small gland ducts.

  • Describe simple columnar epithelium and its special features.

    Single layer of tall cells; may have cilia or microvilli; goblet cells secrete mucus; found in uterine tubes and small intestine.

  • What is pseudostratified columnar epithelium?

    Single layer that appears multi-layered; often ciliated with goblet cells; found in upper respiratory tract.

  • Where is stratified squamous epithelium found and what is its function?

    Multiple layers of flat cells; protects areas of wear and tear like skin, oral cavity, vagina, and anus.

  • What distinguishes stratified cuboidal and stratified columnar epithelium?

    Stratified cuboidal is rare, usually two layers thick; stratified columnar has columnar apical layer and cuboidal deeper layers; both found in ducts and urethra.

  • What is transitional epithelium and its function?

    Lines hollow urinary organs; designed to stretch and return to normal size to accommodate urine volume changes.

  • What are the two main types of glands in glandular epithelium?

    Exocrine glands secrete onto surfaces or cavities via ducts; endocrine glands secrete hormones into blood or tissue fluid without ducts.

  • Describe the three modes of secretion in glandular epithelium.

    Merocrine: exocytosis of secretions; Apocrine: release with apical cytoplasm shedding; Holocrine: entire cell ruptures releasing contents.

  • What are the main functions of connective tissue?

    Binding/supporting tissues, protection, insulation, transport, and energy storage.

  • What are the 'blast' and 'cyte' cells in connective tissue?

    Blast cells are immature cells that build matrix; cyte cells are mature cells that maintain matrix.

  • Name the main types of connective tissue proper.

    Loose connective tissue: areolar, adipose, reticular; Dense connective tissue: dense regular, dense irregular, elastic.

  • What is areolar connective tissue and its function?

    Most widely distributed loose connective tissue; binds and supports other tissues; holds interstitial fluid.

  • What distinguishes white fat from brown fat in adipose tissue?

    White fat stores nutrients and is highly vascularized; brown fat generates heat, more common in babies.

  • What is the role of reticular tissue?

    Forms internal framework supporting white blood cells in lymph nodes, spleen, and bone marrow.

  • What are the characteristics of dense regular connective tissue?

    Parallel collagen fibers; withstands tension in one direction; found in tendons and ligaments; poorly vascularized.

  • How does dense irregular connective tissue differ from dense regular?

    Collagen fibers arranged irregularly; resists tension in multiple directions; found in dermis and joint capsules.

  • Where is elastic connective tissue found and what is its function?

    Contains many elastic fibers; found in elastic ligaments of vertebral column and large arteries; allows stretch and recoil.

  • What are the main features of cartilage tissue?

    ECM with collagen and elastic fibers in gel-like matrix; tough yet flexible; avascular; chondrocytes in lacunae maintain matrix.

  • Name and describe the three types of cartilage.

    Hyaline: most abundant, glassy appearance; Elastic: more elastic fibers, stretchy; Fibrocartilage: strong, thick collagen fibers.

  • What are the key features of bone tissue?

    Most rigid connective tissue due to mineral salts; supports body, protects organs, stores fat, forms blood cells; osteons are structural units.

  • What makes blood a connective tissue?

    Fluid matrix (plasma) with suspended formed elements (red/white blood cells, platelets); transports nutrients, wastes, gases.

  • What are the three types of muscle tissue and their control?

    Skeletal: voluntary, striated, multinucleate; Smooth: involuntary, non-striated, spindle-shaped; Cardiac: involuntary, striated, branched.

  • What is the function of nervous tissue?

    Conducts electrical impulses, senses environment, processes information; composed of neurons and neuroglial cells.

  • What are the three main types of membranes in the body?

    Cutaneous: skin; Mucous: line open passageways; Serous: line ventral body cavities; plus synovial membranes in joints.

  • What is the difference between regeneration and fibrosis in tissue repair?

    Regeneration: replacement by same tissue, function restored; Fibrosis: replacement by connective tissue, function lost.