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Anatomy & Physiology: Tissue Level of Organization
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What is a tissue?
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What is a tissue?
Tissue
is a group of specialized cells and cell products that perform one or more specific functions.
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What is a tissue?
Tissue
is a group of specialized cells and cell products that perform one or more specific functions.
What are the four basic types of tissue?
Epithelial, connective, muscle,
and
nervous tissues
.
What are the main functions of epithelial tissue?
Covers exposed surfaces, lines internal passageways, forms glands, provides physical protection, controls permeability, sensation, and specialized secretions.
What are the key characteristics of epithelial tissue?
Polarity, cellularity, attachment to basement membrane, avascularity, and regeneration.
What is the function of microvilli in epithelial cells?
Microvilli increase surface area for absorption and secretion, especially in digestive tract regions.
What is the role of cilia in epithelial tissue?
Motile cilia move fluids or secretions over epithelial surfaces, such as mucus in the respiratory tract.
Name the two main types of intercellular connections in epithelial tissue.
Cell adhesion molecules (CAMs) and cell junctions.
What are cell adhesion molecules (CAMs)?
Transmembrane proteins that attach opposing plasma membranes and connect cells to extracellular materials.
List the three most common types of cell junctions.
Gap junctions, tight junctions, and desmosomes.
What is the function of gap junctions?
Hold cells together via connexons and allow small molecules and ions to pass between cells.
How do tight junctions function?
They tightly bind plasma membranes to prevent water and solutes from passing between cells.
What is the function of desmosomes?
Link opposing plasma membranes via CAMs and proteoglycans, connecting to the cytoskeleton to stabilize cell shape.
What are hemidesmosomes?
Structures that attach epithelial cells to the basement membrane, resembling half of a desmosome.
How are epithelia classified by cell shape?
Squamous (thin, flat), cuboidal (box-like), and columnar (tall, slender rectangles).
What are the two classifications of epithelia by layers?
Simple (one cell layer) and stratified (multiple cell layers).
Where is simple squamous epithelium found and what is its function?
Found in protected regions like alveoli; functions in absorption and diffusion.
What is the difference between keratinized and nonkeratinized stratified squamous epithelium?
Keratinized has layers packed with keratin for toughness and water resistance; nonkeratinized resists abrasion but must stay moist.
What is transitional epithelium?
A stratified epithelium that appears cuboidal when relaxed and squamous when stretched; found in the urinary bladder.
What distinguishes pseudostratified columnar epithelium?
Appears layered but all cells contact the basement membrane; often ciliated to move mucus.
What are the two types of glandular epithelia?
Endocrine glands (ductless, secrete hormones into blood) and exocrine glands (secrete onto epithelial surfaces or ducts).
What are the three basic components of connective tissue?
Specialized cells, extracellular protein fibers, and ground substance (fluid).
What are the three general categories of connective tissue?
Connective tissue proper, fluid connective tissues, and supporting connective tissues.
What are fibroblasts and their function?
Most abundant fixed cells in connective tissue proper; secrete hyaluronan and protein subunits for collagen, reticular, and elastic fibers.
What are the main fiber types in connective tissue proper?
Collagen fibers (strong, flexible), reticular fibers (branching, flexible framework), and elastic fibers (stretch and recoil).
What is the function of ground substance in connective tissue proper?
A viscous, clear substance that fills spaces between cells and fibers, slowing pathogen movement.
What are the main functions of loose connective tissue?
Fills spaces, cushions organs, supports epithelia, and stabilizes cells.
What distinguishes dense regular from dense irregular connective tissue?
Dense regular has parallel collagen fibers aligned with force direction; dense irregular has interwoven fibers for strength in multiple directions.
What are the characteristics of cartilage as a supporting connective tissue?
Firm gel matrix with chondroitin sulfates; avascular; cells called chondrocytes in lacunae; limited repair ability.
What are the three types of cartilage?
Hyaline (tough, flexible), elastic (supportive, very flexible), and fibrocartilage (durable, shock absorbing).
What makes bone matrix strong and somewhat flexible?
Calcified calcium salts provide hardness; collagen fibers provide strength and flexibility.
What are the three types of muscle tissue?
Skeletal (striated voluntary), cardiac (striated involuntary), and smooth (nonstriated involuntary).
What are the main features of skeletal muscle tissue?
Long, multinucleate fibers; striated; voluntary contraction; limited repair via myosatellite cells.
What are intercalated discs in cardiac muscle?
Specialized connections containing desmosomes, proteoglycans, and gap junctions that coordinate contractions.
What distinguishes smooth muscle tissue?
Nonstriated, involuntary muscle found in walls of blood vessels and hollow organs; capable of regeneration.
What are the two main cell types in nervous tissue?
Neurons (communicative cells) and neuroglia (supporting cells).
What are the main components of a neuron?
Cell body (with nucleus), dendrites (receive information), and axon (conducts electrical signals).