Anatomy & Physiology: Tissue Structure and Function
Termini in questo insieme (27)
A tissue is a group of structurally and functionally related cells that perform a common function together, including the surrounding extracellular matrix (ECM).
The four main tissue types are epithelial, connective, muscle, and nervous tissue.
Tight junctions seal adjacent cells to prevent molecule passage.
Desmosomes anchor cells and distribute mechanical stress.
Gap junctions allow ion and small molecule passage for cell communication.
Epithelial tissue covers body surfaces, forms glands, is tightly packed with little ECM, avascular, innervated, exhibits polarity with apical and basal surfaces, and has high regeneration capacity.
The basement membrane is a boundary between epithelial and connective tissues, composed of the basal lamina (collagen fibers and ground substance) and the reticular lamina (reticular fibers and ground substance).
By layers: Simple (one layer), Stratified (multiple layers).
By shape: Squamous (flat), Cuboidal (cube-shaped), Columnar (tall column-shaped).
Single layer of flat cells with disc-shaped nuclei; functions in diffusion, filtration, and secretion of serous fluid; found in lung alveoli, blood vessels, and serous membranes.
Functions in secretion and absorption; located in kidney tubules, small gland ducts, and ovary surface.
Single layer of tall cells with oval nuclei; may have microvilli or cilia; contains goblet cells for mucus secretion; found lining most of the gastrointestinal tract and some respiratory regions.
Single layer of cells of varying heights, nuclei at different levels, appears stratified but is not; most have cilia and goblet cells; functions in mucus secretion and propulsion; found in respiratory tract and male reproductive ducts.
Multiple layers with basal cells cuboidal or columnar and surface cells squamous; protects against abrasion; keratinized type forms skin surface, nonkeratinized lines moist body openings.
Specialized stratified epithelium with dome-shaped surface cells that stretch; functions in protection and distension; found in urinary bladder, ureters, and part of urethra.
Endocrine glands are ductless, secrete hormones into interstitial fluid and blood.
Exocrine glands secrete onto epithelial surfaces via ducts; include sweat, salivary, and digestive glands.
Unicellular exocrine glands found in respiratory and digestive epithelia; secrete mucin that forms mucus to protect and lubricate surfaces.
Composed of ducts and secretory units; ducts may be simple (unbranched) or compound (branched); secretory cells form tubular, acinar, or tubuloacinar shapes.
Merocrine: secretion via exocytosis.
Holocrine: cells rupture to release product.
Apocrine: product and cytoplasm pinch off from cell surface.
Ground substance (interstitial fluid, glycosaminoglycans, proteoglycans, cell adhesion molecules) and protein fibers (collagen, elastic, reticular fibers).
Collagen fibers: strong, resist tension.
Elastic fibers: stretch and recoil.
Reticular fibers: form supportive networks.
Fibroblasts are cells that produce protein fibers and ground substance of the extracellular matrix in connective tissue.
Loose connective tissue with all three fiber types and various cells; located under epithelia and around organs; functions in cushioning, holding tissue fluid, and inflammation response.
Stores energy as fat, insulates, cushions and protects organs; found under skin and around organs.
Contains parallel collagen fibers and fibroblasts; poorly vascularized; found in tendons and ligaments; resists tension in one direction.
Dense regular has parallel collagen fibers resisting tension in one direction; dense irregular has irregularly arranged fibers resisting tension in multiple directions.
Glossy matrix with fine collagen fibers; chondrocytes in lacunae; avascular; found in fetal skeleton, nose, trachea, and articular surfaces; provides support and reduces friction.
Osteoblasts produce organic matrix that mineralizes; osteocytes reside in lacunae; highly vascularized; provides support, protection, mineral storage, and blood cell formation.
Skeletal muscle: long, multinucleate, striated, voluntary.
Cardiac muscle: branched, uninucleate, striated, involuntary, with intercalated discs.
Smooth muscle: spindle-shaped, uninucleate, nonstriated, involuntary.
Neurons: large excitable cells that transmit electrical signals.
Neuroglia: smaller supporting cells that aid neuron function and maintenance.