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Anatomy & Physiology Unit 1 Key Concepts

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  • Difference between Anatomy and Physiology

    Anatomy studies the structure of body parts and their relationships, while Physiology studies the functions of the body.

  • Complementarity of structure and function

    The function of a body part depends on its specific form. For example, sharp front teeth cut food, flat back teeth grind food, and bones provide support due to hardness.

  • Levels of body organization from smallest to largest

    Atoms → Molecules → Organelles → Cells → Tissues → Organs → Organ systems → Organism

  • Homeostasis

    The ability to maintain relatively stable internal conditions despite changing external environment, usually via negative feedback mechanisms.

  • Negative feedback mechanism

    A response that counteracts the original stimulus to maintain homeostasis, like a thermostat activating a heater when cold.

  • Positive feedback mechanism

    A response that enhances the original stimulus, pushing the system further from the starting point, such as blood clotting.

  • Anatomical position

    Body standing facing observer, head level, feet forward, palms turned forward.

  • Body planes

    Medial (midsagittal) divides left/right, Frontal (coronal) divides front/back, Transverse divides upper/lower.

  • Directional terms: Superior vs Inferior

    Superior (cranial) means toward the head; Inferior (caudal) means toward the lower part of the structure.

  • Major elements of the human body

    Oxygen, Carbon, Hydrogen, Nitrogen make up 96.3% of body weight.

  • Atomic number vs atomic mass

    Atomic number = number of protons; Atomic mass = sum of protons and neutrons.

  • Ionic bond

    Formed by transfer of electrons creating cations and anions attracted by opposite charges, e.g., NaCl.

  • Covalent bond

    Electrons are shared between atoms; can be polar (unequal sharing) or nonpolar (equal sharing).

  • Hydrogen bond

    Weak attraction between a partial positive hydrogen and a partial negative molecule, important for protein shape and DNA structure.

  • Water properties important for life

    High heat capacity, high heat of vaporization, solvent properties, reactivity, and cushioning.

  • Functions of proteins

    Structural material, enzymes, hormones, and cell function regulators; made of amino acids linked by peptide bonds.

  • Enzyme function

    Biological catalysts that lower activation energy to speed up biochemical reactions; act on substrates and are reusable.

  • DNA base pairing rules

    Adenine pairs with Thymine; Guanine pairs with Cytosine.

  • ATP structure and function

    Contains adenine, ribose sugar, and 3 phosphate groups; stores energy in phosphate bonds used for cellular work.

  • Phospholipid bilayer

    Plasma membrane structure with hydrophilic phosphate heads facing outward and hydrophobic fatty acid tails inward.

  • Types of membrane transport

    Passive transport (simple diffusion, facilitated diffusion, osmosis) and active transport (primary, secondary, vesicular).

  • Simple diffusion

    Passive movement of small, lipid-soluble molecules across the membrane without energy or assistance.

  • Facilitated diffusion

    Passive transport of molecules via specific carrier or channel proteins, no energy required.

  • Osmosis

    Diffusion of water across a selectively permeable membrane from high to low water concentration.

  • Tonicity effects on cells

    Isotonic: no change; Hypertonic: cells shrink; Hypotonic: cells swell.

  • Na+/K+ pump

    Primary active transport pump that moves 3 Na+ out and 2 K+ into the cell using ATP, maintaining membrane potential.

  • Phases of mitosis

    Prophase, Metaphase, Anaphase, Telophase; results in two identical daughter cells.

  • Role of mRNA in protein synthesis

    Messenger RNA carries genetic code from DNA in the nucleus to ribosomes in the cytoplasm for translation.

  • Translation elongation steps

    Codon recognition at A-site, peptide bond formation at P-site, ribosome translocation shifting sites, and tRNA exit at E-site.