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Basic Chemistry and Biochemistry in Anatomy & Physiology
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What is a mole in chemistry?
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What is a mole in chemistry?
One mole
equals \(6.022 \times 10^{23}\) particles, known as Avogadro's number.
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Nascondere definizioni
What is a mole in chemistry?
One mole
equals \(6.022 \times 10^{23}\) particles, known as Avogadro's number.
What are the three subatomic particles of an atom?
Protons
(positive charge),
neutrons
(neutral), and
electrons
(negative charge).
What defines an element's atomic number?
The
number of protons
in the nucleus of an atom.
What is the mass number of an atom?
The sum of
protons and neutrons
in the nucleus.
What are inorganic compounds important to the body?
Water, salts, acids, and bases are
inorganic compounds
essential for life.
List five important properties of water.
1. High heat capacity, 2. High heat of vaporization, 3. Polar solvent properties, 4. Reactivity (hydrolysis), 5. Cushioning.
What happens when salts dissolve in water?
They dissociate into
ions called electrolytes
that conduct electrical currents.
Define acids and bases in terms of proton transfer.
Acids
donate protons (H+),
bases
accept protons and release hydroxide ions (OH-).
What is the pH scale and what does it measure?
A
logarithmic scale
measuring hydrogen ion concentration; lower pH is acidic, higher pH is basic.
What is a neutralization reaction?
A strong acid and strong base react to form
salt and water
, neutralizing each other.
What role do buffers play in the body?
Buffers convert strong acids or bases into
weaker ones
to maintain stable pH, e.g., carbonic acid-bicarbonate system.
How are organic compounds synthesized and broken down?
Synthesized by
dehydration synthesis
and broken down by
hydrolysis
reactions.
What are the four main classes of organic macromolecules?
Carbohydrates, lipids, proteins, and nucleic acids.
What are monosaccharides? Give examples.
Simple sugars with one unit, e.g., glucose, fructose, and galactose.
What are disaccharides? Give examples.
Two linked monosaccharides, e.g., sucrose, maltose, and lactose.
What are polysaccharides? Give an example.
Long chains of linked monosaccharides, e.g., glycogen.
What are triglycerides composed of?
Three fatty acids and one glycerol molecule joined by dehydration synthesis.
Difference between saturated and unsaturated fats?
Saturated fats have
no double bonds
between carbons; unsaturated fats have
one or more double bonds
causing kinks.
What is the structure of phospholipids?
Two hydrophobic fatty acid tails and one hydrophilic polar head.
What are steroids? Give an example.
Lipids with four interlocking hydrocarbon rings; cholesterol is a common steroid.
What are the four structural levels of proteins?
Primary (amino acid sequence), secondary (alpha helices and beta sheets), tertiary (3D folding), quaternary (multiple polypeptide chains).
What is protein denaturation?
Loss of protein's native structure due to environmental changes; may be reversible or irreversible.
What is the role of enzymes?
Proteins that
lower activation energy
to speed up biochemical reactions.
What are the three steps of enzyme action?
1. Substrate binds active site, 2. Enzyme-substrate complex undergoes internal rearrangement, 3. Product is released.
What are the structural units of DNA and RNA?
Nucleotides composed of a nitrogenous base, pentose sugar, and phosphate group.
Difference between DNA and RNA bases?
DNA uses thymine (T); RNA uses uracil (U) instead.
What is the structure of DNA?
Double-stranded helix with complementary base pairing: A-T and G-C.
What is ATP and its function?
Adenosine triphosphate; the primary energy carrier transferring energy to other compounds.