Chapter 4 - The Integumentary System (Exam I)
Termini in questo insieme (53)
The integumentary system has the following functions:
___ from environmental hazards, trauma, chemicals
____ skin permeability
____ water loss
____ pathogen entry
synthesizes ___ and ___
has ___ receptors to ____ info
protects
controls
prevents
stops
vitamin d3 and lipids
sensory; sense
what are the 2 main components of the integumentary system, and what are their components
cutaneous membrane (skin) - epidermis and dermis
accessory structures - hair follicles, exocrine glands, nails
most cells in the epidermis are _____
keratinocytes
the skin (aka cutaneous membrane) has 2 subdivisions:
epidermis is ____ ____ epithelium
Dermis is the underlying ____ CT
stratified squamous
loose
deep to the dermis is the ____ layer
subcutaneous/hypodermis
the superficial layer of the dermis aka ___ layer has what type of connective tissue?
papillary
LACT
The deep layer of the dermis aka ____ layer has what type of connective tissue
reticular
DICT
the deep epidermis has what type of tissue in it? which layer
living (basale)
what are the 5 layers of thick-skinned epidermis? (from deep to most superficial)
which layer is not in thin skin?
stratum basale (germinativum)
stratum spinosum
stratum granulosum
stratum lucidium (not in thin skin)
stratum corenum
what are the 4 cell types of epidermis
keratinocytes
melanocytes
merkel cells
Langerhans
____ are the most abundant cells in the epidermis
keratinocytes
____ are pigment cells found deep in the epidermis
melanocytes
___ are sensory cells
Merkel
____ cells are fixed macrophages
Langerhans
the stratum germinativum layer is the most ___ layer of the epidermis
attached to the ____ ____
contains ___ cells that are large stem cells that give rise to new keratinocytes, ____ and ____ cells
innermost/deep
basal lamina
basale, melanocytes, Merkel
The Stratum Spinosum layer of the epidermis contains ____ pushed from basal layer
contains several layers of ____ bound together by ___ ____ attached to ____ of the cytoskeleton
____ cells and ____ are often present in this layer
keratinocytes
keratinocytes, macula adherens (desmosomes), tonofibrils
Langerhans and melanocytes
In the Stratum Granulosum layer of the epidermis, cells still have a ____
keratinocytes start making large amount of protein called ____ and ____
___ ____ develop as cells become thinner and flatter
in this layer, cell membranes ____, organelles ____, and the cells ____
nucleus
keratohyalin & Keratin
keratin fibers
thicken, disintegrate, die
The stratum lucidum layer is a ____ layer
the cells contain no ___ or ____
only appears in ___ skin
glassy
organelles or nuclei
thick
The Stratum Corneum consists of multiple layers of flattened, dead, interlocking _____
typically very ____
____ resistant but not _____
permits slow water loss by ____ ____
keratinocytes
dry
water; water proof
insensible perspiration
keratinization or cornification occurs in all exposed skin surfaces except the anterior surface of the ___
eyes
thick skin only found on ___ and ___
palms (head) and soles (feet)
Dermal ridges form friction ridges (finger prints) and are formed by interlocking of the ____ and ____
stratum basale and dermal papillae
_____ is the projection of dermis toward epidermis that helps create dermal ridges
dermal papillae
melanin is not present in ___ and ____
palms and soles
_____ are intracellular vesicles filled with melanin and most abundant around the ____ of cells
melanosomes
nucleus
____ layer of dermis consists of LACT that provides mechanical ____ for epidermis and contains ___ and ____
papillary
attachment
axons and capillaries
____ layer of dermis contains DICT surrounding blood vessels, hair follicles, nerves, and sweat glands
reticular
collagen and elastic fibers arranged in parallel bundles align to resist applied forces, resulting in a pattern called ____
tension lines
____ is a nonliving keratinized structure that extends beyond the surface of the skin in most are of the body
hair
hair ___ are the organs that form hairs; extend deep into the dermis and sometimes the subcutaneous tissue
follicles
hair ___ is a connective tissue with capillaries and nerves
papilla
_____ is a type of smooth muscle that extends from papillary layer to connective tissue sheath; pulls on hair follicle and raises hair
arrector pili muscle
___ glands are most commonly associated with hair
sebaceous
____ is the bunch of sensory nerves surrounding the base of each hair follicle
root hair plexus
____ are extremely find, unpigmented hair that appears ~3 months into embryonic development; mostly shed before birth
lanugo
____ are "peach fuzz" hairs with no distinct medulla
vellus hairs
____ hairs are heavy and pigmented
terminal hairs
____ is a single layer of dead keratinized cells at the outer surface of hair that overlap
cuticle
white hair is from lower pigments being produced by melanocytes in the ___ of the hair and the presence of air bubbles within the ____
papilla
medulla
Hair growth cycle:
during the active phase, hair grows ___mm/day for about ___ years
during the regression phase, the hair loosens from the follicle and becomes ___ hair
next is the ___ phase
Lastly, during the reactivation phase club hair is ___ and the hair ____ begins producing replacement
0.33/2-5 years
club
resting
lost/matrix
what are the 2 exocrine glands?
sebaceous glands
sweat glands
what are the two sweat glands; what is another name for sweat glands
apocrine glands
merocrine/eccrine glands
Sudoriferous
____ glands produce waxy, oily lipid that coats hair shaft and epidermis
cells of this gland release through ____ secretion (cell ____)
sebaceous
holocrine; ruptures
_____ glands produce watery solution which are squeezed out by specialized epithelial cells called ____ cells
sweat
myoepithelial
____ sweat glands release secretions into hair follicles in armpits, nipples, groin
cells of this gland release through ___ secretion
secretions are usually viscous, cloudy, odorous and begin at ____
apocrine
eccrine (vesicular secretion, not via apocrine secretion!!!)
puberty
____ sweat glands are smaller than apocrine glands and aren't located as deep
produce clear secretion called ____ or ____ _____
excrete ___, ____, and ____
protects us by _____ harmful chemicals and discouraging ____
eccrine/merocrine
sweat or sensible perspiration
water, electrolytes, and drugs
diluting; bacteria
the entire epidermis is called what?
keratinized stratified squamous epithelium
What are the primary cells in the epidermis
keratinocytes
which layer of the epidermis is simple cuboidal epithelium and is the actively mitotically dividing layer?
stratum basale/germinativum
which layer of the epidermis contained laminated granules and gives skin its water resistance?
stratum granulosum
what are all the names for the layer beneath the reticular layer of the dermis?
hypodermis
adipose layer
subcutaneous layer
camper's fascia
superficial fascia
___ fascia connects one part of the body to another. ____ fascia does NOT
deep
superficial
____ secrete sebum onto the skin surface. ___ secretes sebum into hair follicles
sebaceous follicle
sebaceous gland