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Indietro

Chapter 5 - The Skeletal System: Osseous Tissue and Skeletal Structure - Exam I

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  • The skeletal system is made up of what components


    skeleton

    cartilages

    ligaments

    other CT that stabilize them

  • what is the major component of the skeletal system


    bone tissue OR osseous tissue

  • Is the bone highly vascularized and innervated?


    yes

  • List the 5 functions of the skeletal system


    Support (body's infrastructure)

    Storage of minerals (98% of calcium in bones)

    Blood cell production

    Protection (surrounds many delicate organs)

    Leverage (muscles pull on bone to produce movement)

  • Structure of BONE (aka ___):

    ____ connective tissue

    outer covering called ____ that's made of _____

    inner cellular lining called the ____


    osseous tissue

    supporting

    periosteum; DICT

    endosteum

  • the periosteum is continuous with the ____ fascia, NOT the ____ fascia


    deep; superficial

  • the periosteum holds onto the bone via ____


    Sharpey's fibers

  • The matrix of mature bones is called what?


    osteoid

  • What is the matrix made of in mature bones?


    2/3 calcium phosphate (hydroxyapatite)

    1/2 collage fibers

  • what are the cells found in mature bones


    osteocytes

    osteoblasts

    osteoprogenitor cells (won't ask about this)

    osteoclasts

  • which bone cell is a mature cell that maintains bone tissue


    osteocyte

  • which cell is an immature, active cell of the bone that's found in inner and outer surfaces of bone.

    What do these cells produce?


    osteoblasts

    osteoid (matrix)

  • ____ are giant multinucleated cells that break down osteoid and release calcium and phosphate


    osteoclasts

  • Perforating or ____ canals extend ____ to the surface of the bone and connects ____ to one another


    Volkman's

    perpendicular

    osteons

  • _____ fill in spaces between osteons of compact bones


    interstitial lamellae

  • ____ form outer and inner rings on surface of shaft


    circumferential lamallae

  • osteons and central canals are only present in ___ bones


    compact

  • which structures of the bone are present in both spongy and compact bone?


    lacunae

    lamellae

  • ____ are channels that radiate through the matrix and connect lacuna to one another


    canaliculi

  • ____ are the rings found around central canals in osteons


    concentric lamellae

  • a single ___ resides inside a lacunae of bone tissue


    osteocyte

  • spongy bone aka ___ or ____


    trabeculae

    cancellous

  • ____ spiral around concentric lamellae at opposite angles, creating a very strong structure


    collagen

  • What are the 3 different parts of long compact bones


    epiphyses

    diaphysis

    metaphysis (endochondral or epiphyseal growth plate)

  • the ____ is the shaft of a long bone


    diaphysis

  • the ___ are the ends of a long bone


    epiphyses

  • the ___ is the layer that connects the epiphyses and diaphysis


    metaphysiis

  • The ____ serves several functions:

    ____ and ____ the bone from surrounding tissue

    provides a ____ and a place of ___ circulatory and nervous supply

    actively participates in bone ____ and ____ by having cells that will become osteoblasts

    attaches the ____ to the ____


    periosteum

    isolates and protects

    route; attachment

    growth and repair

    connective tissue; deep fascia

  • what are the 2 layers of the periosteum


    fibrous layer (dense fibrous CT)

    cellular layer (contains osteoprogenitor cells)

  • ___ is bone formation

    ____ is the process of depositing calcium salts into tissues


    osteogenesis

    calcification

  • what are the two ways that ossification occurs? Which one makes most of our bones?


    Intramembranous ossification

    Endochondral ossification (main one)

  • which bones are made via intramembranous ossification


    skull, roofing bones of skull, part of mandible

    clavicles

  • Intramembranous ossification

    1. ____ cells aggregate, differentiate into ____, and begin the ossification process. The bone expands as a series of ____ that spread into surrounding tissue


    mesenchymal; osteoblasts; spicules

  • Steps of Intramembranous Ossification

    1. As the spicules ____, they trap ___ within the bone


    interconnect; blood vessels

  • Steps of the Intramembranous ossification

    1. Over time, the bone assumes the structure of ___ bone. Areas of this region may later be removed, creating _____. Through remodeling, spongy bone may be converted into ____ bone.


    spongy; medullary cavities; compact

  • Endochondral Ossification

    1. As the cartilage enlarges, ___ near the center of the shaft increase in size. The ___ is reduced to a series of small ___ that soon begin to ___. The enlarged ____ then die and disintegrate, leaving ____ within the cartilage.


    chondrocytes

    matrix; struts; calcify

    chondrocytes; cavities

  • Endochondral Ossification

    1. ___ grow around the edges of the cartilage, and the cells of the ____ convert into ____. The shaft of the cartilage the becomes ensheathed in a superficial layer of ____


    blood vessels

    periosteum

    osteoblasts

    bone

  • Endochondral ossification

    1. Blood vessels penetrate the ____ and invade the _____. ____ migrating with the blood vessels differentiate into ____ and begin producing ____ bone at its primary center of ossification. Bone formation then spreads along the ____ towards the ____


    cartilage; central region

    Fibroblasts; osteoblasts; spongy

    shaft; ends

  • Endochondral Ossification

    1. Remodeling occurs as growth continues, creating a _____. The bone of the shaft becomes ___, and the cartilage near each epiphysis is replaced by shafts of ____. Further growth involves increases in ____ and ____


    medullary cavity

    thicker

    bone

    length and diameter

  • Endochondral ossification

    1. ___ and ____ migrate into the ____, creating a secondary ossification center


    capillaries and osteoblasts

    epiphyses

  • Endochondral ossification

    1. Soon the epiphyses are filled with ____ bone. An ____ cartilage remains exposed to the joint cavity; over time it will be reduced to a thin superficial layer. At each metaphysis, an _____ cartilage separates the epiphysis from the diaphysis


    spongy

    articular

    epiphyseal

  • ____ is a distinct line indicating the former location of epiphyseal cartilage


    epiphyseal line

  • When infants are growing adult bones, what type of growth do they go through? Please describe it


    appositional growth (diameter enlarges though growth at the outer surface of bone)

  • What are the ions and vitamins that typically regulate bone growth


    Ions: calcium, phosphate, Mg, citrate, carbonate, sodium

    Vitamins: A, C, and D (needed to absorb calcium and phosphate in blood)

  • ____ acts to increase the overall availability of calcium ions in the blood via increased ____ activity

    ___ is the antagonist of the above and inhibits ____ activity


    Parathyroid hormone (PTH); osteoclasts

    calcitonin; osteoclasts

  • Name the epiphyseal plate growth zones


    Resting cartilage

    Proliferating cartilage

    Hypertrophic cartilage

    Calcified cartilage

    Ossification

  • Describe zone of resting cartilage


    cartilage attaches to the epiphyses

  • Describe zone of proliferating cartilage


    new cartilage is produced on the epiphyseal side of the plate as chondrocytes divide and form stacks of cells

  • Describe zone of hypertrophy


    chondrocytes mature and enlarge

  • Describe zone of calcification


    matrix is calcified and chondrocytes die

  • Describe ossification of bone after growth


    calcified cartilage on the diaphyseal side of the plate is replaced by bone