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Nervous System Anatomy & Physiology Flashcards
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What happens first when an action potential reaches the axon terminal?
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What happens first when an action potential reaches the axon terminal?
Voltage-gated calcium (Ca²⁺) channels open, allowing calcium to enter the neuron.
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What happens first when an action potential reaches the axon terminal?
Voltage-gated calcium (Ca²⁺) channels open, allowing calcium to enter the neuron.
Why is calcium important during nerve transmission?
Calcium causes synaptic vesicles to fuse with the presynaptic membrane, releasing neurotransmitters into the synaptic cleft.
What are synaptic vesicles?
Small membrane-bound sacs in the axon terminal that store neurotransmitters like acetylcholine.
What is acetylcholine (ACh)?
A neurotransmitter that carries signals across synapses and stimulates skeletal muscle contraction.
What is the synaptic cleft?
The tiny gap between the presynaptic neuron and postsynaptic cell where neurotransmitters diffuse.
What is the postsynaptic cell?
The cell that receives neurotransmitters; can be a neuron, muscle cell, or gland cell.
Where do neurotransmitters bind after crossing the synaptic cleft?
To specific receptors on the postsynaptic membrane, initiating a response.
What triggers synaptic vesicles to release acetylcholine?
Calcium entering the axon terminal triggers vesicles to fuse with the membrane and release acetylcholine by exocytosis.
What occurs at the synapse?
Chemical communication between two cells via neurotransmitter release.
What is the function of dendrites?
To receive incoming signals from other neurons and carry them toward the cell body.
What is the function of the cell body (soma)?
Contains the nucleus and organelles; serves as the neuron's metabolic center.
What is the function of the axon?
Conducts nerve impulses away from the cell body toward other neurons, muscles, or glands.
What is the function of the myelin sheath?
Insulates the axon and greatly increases the speed of nerve impulse conduction.
What are Nodes of Ranvier?
Gaps between myelin segments where action potentials are regenerated for saltatory conduction.
What is the function of the axon terminal?
Stores and releases neurotransmitters to communicate with the next cell.
What is the function of astrocytes?
Provide structural support, maintain the blood-brain barrier, regulate extracellular environment, and assist in repair.
Where are astrocytes located?
In the central nervous system (CNS).
What is the function of oligodendrocytes?
Produce myelin sheath around CNS axons; one can myelinate multiple axons.
What is the function of Schwann cells?
Produce myelin sheath around PNS axons and assist with nerve regeneration.
What is the function of ependymal cells?
Line brain ventricles and spinal cord central canal; help produce and circulate cerebrospinal fluid (CSF).
What is the primary function of neurons?
To receive, process, and transmit electrical signals throughout the nervous system.
Do mature neurons normally divide?
No, mature neurons are amitotic and generally do not undergo cell division.
Why do neurons have a high metabolic rate?
They require continuous oxygen and glucose to produce ATP for nerve impulse conduction.
What structures make up the central nervous system (CNS)?
The brain and spinal cord.
What does norepinephrine do?
Involved in the sympathetic nervous system; increases heart rate, blood pressure, and alertness.
What does dopamine do?
Involved in movement, motivation, reward, learning, and pleasure.
What does serotonin do?
Regulates mood, sleep, appetite, and emotional well-being.
What is a tract?
A bundle of axons located in the central nervous system (CNS).
What is a nerve?
A bundle of axons located in the peripheral nervous system (PNS).
What is a ganglion?
A collection of neuron cell bodies in the peripheral nervous system (PNS).
What is a nucleus in the nervous system?
A collection of neuron cell bodies in the central nervous system (CNS).
Difference between a tract and a nerve?
A tract is a bundle of axons in the CNS; a nerve is a bundle of axons in the PNS.
Difference between a ganglion and a nucleus?
A ganglion is neuron cell bodies in the PNS; a nucleus is neuron cell bodies in the CNS.