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General Biology: Biomolecules and Macromolecules

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  • What are the four main classes of biological macromolecules?

    Nucleic acids, Proteins, Carbohydrates, and Lipids.
  • What is a polymer and what are its building blocks?

    A polymer is a large molecule made of repeating smaller units called monomers.
  • What process builds polymers from monomers?

    Dehydration synthesis (condensation) removes water to form bonds between monomers.
  • What process breaks polymers into monomers?

    Hydrolysis adds water to break bonds and release monomers.
  • Why is carbon essential in biological molecules?

    Carbon can form four bonds, branch in multiple directions, and create diverse molecular shapes.
  • What is a functional group in organic molecules?

    A functional group is a specific group of atoms that participates in chemical reactions and determines molecule properties.
  • Name three important functional groups in biomolecules.

    Hydroxyl (-OH), Carboxyl (-COOH), and Amino (-NH2) groups.
  • What is the monomer and polymer of proteins?

    Monomer: Amino acid; Polymer: Polypeptide or Protein.
  • What type of bond links amino acids in proteins?

    Peptide bonds formed by dehydration synthesis link amino acids.
  • What determines the folding and function of a protein?

    The chemical properties of the side chains (R groups) determine protein folding and function.
  • What are the four levels of protein structure?

    Primary (amino acid sequence), Secondary (alpha helices and beta sheets), Tertiary (3D folding), and Quaternary (multi-subunit assembly).
  • How can changes in pH or temperature affect proteins?

    They can cause denaturation, disrupting hydrogen and ionic bonds, leading to loss of structure and function.
  • What are nucleic acids made of?

    Polymers of nucleotides, each containing a sugar, phosphate group, and nitrogenous base.
  • What is the difference between DNA and RNA sugars?

    DNA contains deoxyribose (lacking an -OH at 2' carbon), RNA contains ribose with an -OH at 2'.
  • What bases are found in DNA and RNA?

    DNA: A, T, C, G; RNA: A, U, C, G (Uracil replaces Thymine).
  • How do nucleotides link to form nucleic acids?

    Via phosphodiester bonds between the 5' phosphate and 3' hydroxyl groups.
  • What is the directionality of nucleic acid strands?

    Strands run 5' to 3' direction, with antiparallel complementary strands in DNA.
  • What is the role of ATP in cells?

    Adenosine Triphosphate (ATP) is the main energy currency, providing energy for cellular processes.
  • What is the molecular formula of glucose?

    C6H12O6.
  • What is the formula of a disaccharide formed by two glucose molecules via dehydration synthesis?

    C12H22O11 (loss of one water molecule).