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General Biology: Fundamentals of Life and Cells

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  • Definition of life (NASA, Joyce 1995)

    Life is a self-sustained chemical system capable of undergoing Darwinian evolution.

  • Key properties of life

    Life is membrane delimited, made of cells, stores and follows instructions, stores and uses energy, is self-replicating, controls functions and responds to the environment, and evolves.

  • Why are lipids important for life?

    Lipids form membranes that provide a selectively permeable barrier, enabling compartmentation and energy storage.

  • Role of nucleic acids in life

    Nucleic acids store and transmit genetic information essential for replication and function.

  • What biomolecules facilitate life’s self-replication?

    All major biomolecules (lipids, carbohydrates, nucleic acids, proteins) facilitate self-replication.

  • How does life store and use energy?

    Energy from sunlight or organic compounds is converted into ATP, which cells use to perform work.

  • What biomolecules control life’s functions and responses?

    Proteins facilitate control of cellular functions and responses to the environment.

  • Definition of evolution in biology

    Evolution is the change in heritable characteristics of biological populations over successive generations.

  • Smallest unit that meets all properties of life

    The cell is the smallest unit that exhibits all properties of life.

  • Characteristics of prokaryotic cells

    Prokaryotes have no nucleus, circular DNA, small size (0.1-5 microns), often lack membrane-bound organelles, and replicate quickly.

  • Characteristics of eukaryotic cells

    Eukaryotes have a nucleus, membrane-bound organelles, linear DNA organized in chromosomes, and are larger (1-100 microns).

  • Are viruses alive?

    Viruses store and follow instructions, use energy, replicate, respond, and evolve, but lack membranes and do not store energy independently.

  • Monomers and polymers of carbohydrates

    Monomers are monosaccharides like glucose; polymers include disaccharides and polysaccharides like glycogen.

  • Structure of amino acids

    Amino acids have an amino group, carboxyl group, hydrogen, and variable side chain (R group) attached to a central carbon.

  • Peptide bond formation

    A peptide bond forms between amino acids by a dehydration reaction linking the carboxyl group of one to the amino group of another.

  • Protein secondary structures

    Common secondary structures include alpha helices and beta sheets, stabilized by hydrogen bonds.

  • Function of ATP in cells

    ATP stores and transfers energy within cells to power biological processes.

  • Role of carbohydrates in energy storage

    Carbohydrates serve as energy sources and structural components in cells.

  • Difference between saturated and unsaturated fatty acids

    Saturated fatty acids have no double bonds; unsaturated fatty acids have one or more double bonds affecting membrane fluidity.

  • Why is membrane compartmentalization important?

    Membranes create distinct environments for cellular processes, enabling regulation and efficiency.