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General Biology Key Concepts

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  • Properties of life

    Living things are made of cells, use energy (metabolism), maintain homeostasis, grow and develop, reproduce, respond to the environment, and evolve over time.

  • Cell Theory

    All living organisms are made of cells; the cell is the basic unit of life; all cells come from preexisting cells.

  • Natural Selection

    Individuals vary; some traits help survival and reproduction; beneficial traits become more common over generations in populations.

  • Adaptation

    An inherited trait that improves survival or reproduction in a specific environment, like polar bear fur or cactus water storage.

  • Chromosome Theory of Inheritance

    Genes are located on chromosomes, which carry genetic information passed from parents to offspring.

  • Central Dogma of Molecular Biology

    Flow of genetic information: DNA is transcribed into RNA, which is translated into protein.

  • Importance of Mutations

    Mutations are changes in DNA sequence that create genetic variation, essential for evolution.

  • Phylogenetic Tree

    Shows evolutionary relationships, common ancestors, and relatedness among species.

  • Why organisms need to eat

    For energy to power metabolism and cellular work, and raw materials to build and repair cells.

  • Atom, Element, and Isotope

    Atom: smallest unit of matter; Element: substance of one atom type; Isotope: atoms of same element with different neutrons.

  • Subatomic particles of an atom

    Protons (positive, in nucleus), Neutrons (neutral, in nucleus), Electrons (negative, orbit nucleus).

  • Atomic number and mass number

    Atomic number = number of protons; Mass number = protons + neutrons.

  • Valence shell

    The outermost electron shell; valence electrons determine chemical bonding.

  • Three main chemical bonds

    Covalent (shares electrons), Ionic (transfers electrons), Hydrogen (weak attraction between polar molecules).

  • Properties of water

    Polar, cohesion, adhesion, high specific heat, excellent solvent, expands when frozen; important for temperature regulation and chemical reactions.

  • Acids, bases, and buffers

    Acids release H⁺ (pH < 7), bases accept H⁺ or release OH⁻ (pH > 7), buffers resist pH changes to maintain stability.

  • Organic compounds

    Carbon-containing molecules essential for life: carbohydrates, lipids, proteins, nucleic acids.

  • Why carbon is the base of organic compounds

    Carbon has four valence electrons and can form four covalent bonds, allowing diverse complex molecules.

  • Isomer

    Compounds with the same molecular formula but different structures, leading to different functions.

  • Polymers and monomers

    Monomers are small building blocks; polymers are many monomers linked together, e.g., amino acids form proteins.

  • Dehydration synthesis and hydrolysis

    Dehydration synthesis removes water to build polymers; hydrolysis adds water to break polymers apart.

  • Amino acid structure

    Contains an amino group (NH₂), carboxyl group (COOH), hydrogen, R-group (side chain), and central carbon.

  • Peptide bond

    Bond between two amino acids linking them into protein chains.

  • Four levels of protein structure

    Primary: amino acid sequence; Secondary: alpha helices and beta sheets; Tertiary: 3D shape; Quaternary: multiple polypeptide chains.

  • Functions of proteins

    Act as enzymes, transport molecules, provide structure, allow movement, send signals, and defend against disease.

  • Denaturation

    Loss of protein shape caused by heat, pH changes, chemicals, or salt changes, resulting in loss of function.

  • Nucleotide structure

    Composed of a phosphate group, five-carbon sugar, and nitrogenous base.

  • DNA vs RNA

    DNA: double-stranded, deoxyribose sugar, thymine, stores genetic info; RNA: single-stranded, ribose sugar, uracil, involved in protein synthesis.

  • Carbohydrates structure and function

    Made of C, H, O; provide quick energy, energy storage, and structural support (e.g., glucose, starch, cellulose).

  • Membrane components: fats, phospholipids, steroids

    Fats store energy; phospholipids form membranes; steroids act as hormones and stabilize membranes.

  • Phospholipid bilayer

    Hydrophilic heads face water; hydrophobic tails face inward, forming a bilayer that is the membrane's main structure.

  • Fluid Mosaic Model

    Membrane is a flexible phospholipid bilayer with embedded moving proteins allowing transport and communication.

  • Diffusion

    Movement of molecules from high to low concentration without energy.

  • Osmosis

    Diffusion of water across a selectively permeable membrane.

  • Tonicity effects on cells

    Hypertonic: water leaves, cell shrinks; Hypotonic: water enters, cell swells; Isotonic: no net water movement.

  • Active transport

    Movement of substances against concentration gradient (low to high) using ATP and transport proteins.

  • Endocytosis and Exocytosis

    Endocytosis: cell takes in materials via vesicles; Exocytosis: cell releases materials via vesicles.