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General Biology Key Concepts

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  • Define matter, atom, ion, molecule, and compound

    Matter is anything that has mass and takes up space. An atom is the smallest unit of an element. An ion is an atom or molecule with a charge. A molecule is two or more atoms bonded together. A compound is a molecule made of different elements.

  • Parts of an atom and their charges

    Protons (positive charge) and neutrons (neutral) are in the nucleus. Electrons (negative charge) orbit the nucleus.

  • Information from the periodic table

    The periodic table shows atomic number (protons), atomic mass, and electronegativity of elements.

  • What are emergent properties? Give an example.

    Emergent properties are new traits that arise from the interaction of parts. Example: Water's ability to moderate temperature arises from hydrogen bonding.

  • Define essential elements and name the four main ones

    Essential elements are required for life. The four main ones are carbon (C), hydrogen (H), oxygen (O), and nitrogen (N).

  • Difference between atomic number and mass number

    Atomic number is the number of protons. Mass number is the sum of protons and neutrons in the nucleus.

  • What are valence electrons and why are they important?

    Valence electrons are electrons in the outer shell; they determine an atom's chemical reactivity and bonding.

  • Describe the three main chemical bonds

    Ionic bonds transfer electrons, covalent bonds share electrons, and hydrogen bonds are weak attractions between polar molecules.

  • Define electronegativity

    Electronegativity is an atom's ability to attract electrons in a bond.

  • Why do most atoms want to react with each other?

    Atoms react to fill their outer electron shells and achieve a stable electron configuration.

  • Explain the polarity of water

    Water is polar because oxygen is more electronegative than hydrogen, creating partial charges.

  • Define cohesion, adhesion, and surface tension

    Cohesion is water molecules sticking to each other, adhesion is water sticking to other surfaces, and surface tension is the resistance of water's surface to external force.

  • How does water moderate temperature? Define specific heat

    Water absorbs heat without large temperature changes due to its high specific heat, stabilizing environments.

  • Why does ice float on water?

    Ice is less dense than liquid water because hydrogen bonds form a lattice that spaces molecules apart.

  • Differentiate solution, solvent, and solute

    A solution is a homogeneous mixture, the solvent dissolves substances, and the solute is dissolved.

  • Define hydrophobic and hydrophilic

    Hydrophobic molecules repel water (nonpolar), while hydrophilic molecules attract water (polar or charged).

  • Define acid, base, and explain pH scale

    Acids increase hydrogen ion concentration, bases decrease it. The pH scale measures acidity from 0 (acidic) to 14 (basic).

  • What is a buffer and how does it work?

    A buffer stabilizes pH by absorbing or releasing hydrogen ions to resist changes.

  • What are hydrocarbons and why are they biologically important?

    Hydrocarbons are molecules of only carbon and hydrogen; they store energy and form the backbone of organic molecules.

  • Define monomers and polymers

    Monomers are small building blocks; polymers are chains of monomers linked by covalent bonds.

  • Name the four classes of macromolecules

    The four classes are carbohydrates, lipids, proteins, and nucleic acids.

  • Explain condensation reaction and hydrolysis

    Condensation links monomers by removing water; hydrolysis breaks polymers by adding water.

  • Difference between monosaccharide, disaccharide, and polysaccharide

    Monosaccharides are single sugars, disaccharides are two sugars linked, and polysaccharides are long chains of sugars.

  • Describe the four levels of protein structure

    Primary: amino acid sequence; secondary: alpha helices and beta sheets; tertiary: 3D folding; quaternary: multiple polypeptide chains.

  • How do saturated, unsaturated, and trans fats differ structurally?

    Saturated fats have no double bonds, unsaturated fats have one or more double bonds, and trans fats have artificially hydrogenated double bonds.

  • What is an amphipathic molecule?

    An amphipathic molecule has both hydrophilic (polar) and hydrophobic (nonpolar) parts.

  • Describe the structure of a nucleotide

    A nucleotide has a sugar, phosphate group, and nitrogenous base; variations occur in the base and sugar.

  • What does 5’ and 3’ mean in nucleic acid structure?

    5’ and 3’ refer to the carbon numbers in the sugar; nucleotides link 5’ phosphate to 3’ hydroxyl forming the backbone.

  • Differences between prokaryotic and eukaryotic cells

    Prokaryotes lack a nucleus and membrane-bound organelles; eukaryotes have both.

  • What is the endomembrane system and its organelles?

    The endomembrane system includes the nuclear envelope, ER, Golgi apparatus, lysosomes, vesicles, and plasma membrane, coordinating protein and lipid transport.

  • Describe the endosymbiotic theory

    The theory that mitochondria and chloroplasts originated from free-living prokaryotes engulfed by ancestral eukaryotic cells.

  • Main components and functions of the cytoskeleton

    The cytoskeleton includes microtubules (shape, transport), microfilaments (movement, support), and intermediate filaments (structural stability).

  • Why is the extracellular matrix important?

    The extracellular matrix provides structural support, mediates cell communication, and influences cell behavior.