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General Biology Key Concepts

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  • 7 Characteristics of Life

    Complex organized structure, acquire material and energy, maintain structure and regulate internal environment, respond to stimuli, growth, reproduction, and ability to evolve.

  • Levels of Biological Organization

    From smallest to largest: Subatomic particles → Atoms → Molecules → Organelles → Cells → Tissues → Organs → Organ systems → Multicellular organisms → Populations → Community → Ecosystem → Biosphere.

  • Homeostasis

    The tendency of life to maintain structure and regulate the internal environment, e.g., sweating to cool the body.

  • Difference between Asexual and Sexual Reproduction

    Asexual: one parent, offspring genetically identical. Sexual: two parents, offspring with combined genetic material.

  • Natural Selection

    Survival and reproduction of the fittest members of a population, leading to evolution by passing genes to future generations.

  • Atomic Number vs Atomic Weight

    Atomic number: number of protons. Atomic weight: protons + neutrons.

  • Isotopes

    Atoms of the same element with different numbers of neutrons, resulting in different atomic weights.

  • Ionic vs Covalent Bonds

    Ionic: attraction between oppositely charged ions after electron transfer. Covalent: atoms share electrons.

  • Polar vs Nonpolar Covalent Bonds

    Polar: unequal sharing of electrons, resulting in partial charges. Nonpolar: equal sharing of electrons.

  • Hydrogen Bonds

    Weak attractions between polar molecules where a hydrogen atom covalently bonded to one atom is attracted to another atom.

  • Properties of Water

    Water is polar, has high cohesion and surface tension, high specific heat, high heat of vaporization, and expands when frozen.

  • Hydrophilic vs Hydrophobic

    Hydrophilic: substances that dissolve in water (polar/ionic). Hydrophobic: substances that do not dissolve in water (nonpolar).

  • pH Scale

    Measures acidity from 0 to 14; pH < 7 acidic, pH = 7 neutral, pH > 7 basic; logarithmic scale where 1 unit change = 10× change in H+ concentration.

  • Functional Groups in Organic Molecules

    Seven main groups: Hydroxyl (-OH), Carbonyl (C=O), Carboxyl (-COOH), Amino (-NH2), Sulfhydryl (-SH), Phosphate (-PO4), Methyl (-CH3).

  • Dehydration Synthesis vs Hydrolysis

    Dehydration synthesis: joins monomers by removing water. Hydrolysis: breaks polymers by adding water.

  • Monosaccharides, Disaccharides, Polysaccharides

    Monosaccharides are simple sugars (e.g., glucose). Disaccharides are two monosaccharides joined (e.g., sucrose). Polysaccharides are long chains (e.g., starch, glycogen, cellulose).

  • Four Levels of Protein Structure

    Primary: amino acid sequence; Secondary: helices and sheets stabilized by H bonds; Tertiary: 3D folding from side chain interactions; Quaternary: multiple polypeptide subunits.

  • Denaturation

    Unfolding of protein structure due to disruption of weak interactions, potentially losing function.

  • Nucleic Acids Composition

    Polymers of nucleotides, each with a sugar, phosphate group, and nitrogenous base; DNA has deoxyribose and is double-stranded; RNA has ribose and is single-stranded.

  • Lipids Characteristics

    Mostly nonpolar, hydrophobic molecules including fats, oils, waxes, phospholipids, and steroids; important for energy storage and membranes.

  • Saturated vs Unsaturated Fatty Acids

    Saturated: no double bonds, solid at room temperature. Unsaturated: one or more double bonds, liquid at room temperature.

  • Phospholipid Structure

    Glycerol + 2 fatty acids (hydrophobic tails) + phosphate group (hydrophilic head); form bilayers in water.

  • Plasma Membrane Functions

    Isolates cell contents, regulates material flow, and allows communication with other cells.

  • Differences Between Prokaryotes and Eukaryotes

    Prokaryotes lack nucleus and membrane-bound organelles; DNA in nucleoid. Eukaryotes have nucleus, organelles, and compartmentalization.

  • Mitochondria Features

    Double membrane organelle producing ATP; contains DNA and ribosomes; inner membrane folds called cristae.

  • Chloroplast Features

    Site of photosynthesis; double membrane; contains chlorophyll, DNA, ribosomes; thylakoids and grana inside.

  • Endoplasmic Reticulum Types and Functions

    Rough ER: has ribosomes, synthesizes proteins. Smooth ER: no ribosomes, synthesizes lipids.

  • Golgi Apparatus Functions

    Modifies, sorts, packages, and ships proteins and lipids; has cis (receiving) and trans (shipping) faces.

  • Lysosome Functions

    Digestive organelles for intracellular digestion, recycling cellular material, and programmed cell death.

  • Protein Synthesis and Shipping Pathway

    Ribosome → Rough ER → Vesicle → Golgi apparatus → Vesicle → Plasma membrane → Outside cell.