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General Biology Module 1 Study Guide

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  • Prokaryotic cells

    Cells without a membrane-bound nucleus; DNA is located in the nucleoid region. Examples include bacteria and archaea.

  • Eukaryotic cells

    Cells with a membrane-bound nucleus containing most of their DNA.

  • Central dogma of molecular biology

    The flow of genetic information from DNA to RNA to protein.

  • Transcription

    Process of making RNA using DNA as a template.

  • Translation

    Process where mRNA is used to build a polypeptide (protein).

  • Covalent bond

    A chemical bond formed when atoms share electrons; can be nonpolar (equal sharing) or polar (unequal sharing).

  • Ionic bond

    Attraction between oppositely charged ions formed after electron transfer.

  • Hydrogen bond

    Weak attraction between a partially positive hydrogen and an electronegative atom like oxygen or nitrogen.

  • Polarity in water

    Unequal distribution of electrical charge; oxygen is partially negative (δ−) and hydrogens are partially positive (δ+).

  • Cohesion

    Attraction between molecules of the same substance, such as water molecules sticking together.

  • Adhesion

    Attraction between molecules of different substances, like water molecules sticking to plant vessel walls.

  • Macromolecule

    A large molecule built from smaller subunits, such as carbohydrates, lipids, proteins, and nucleic acids.

  • Monomer vs. Polymer

    Monomer: small molecular subunit; Polymer: large molecule made of linked monomers.

  • Carbohydrates main functions

    Energy, energy storage, and structural support.

  • Dehydration synthesis

    Joins molecules by removing water, building larger biological molecules.

  • Hydrolysis

    Breaks chemical bonds by adding water, breaking down molecules.

  • Saturated vs. unsaturated fatty acids

    Saturated have no double bonds and pack tightly; unsaturated have double bonds causing bends that lower melting points.

  • Phospholipid structure

    Molecule with hydrophilic head and hydrophobic tails; forms bilayers in water with tails inward.

  • Protein primary structure

    Specific amino acid sequence connected by peptide bonds.

  • Protein denaturation

    Change in protein shape causing loss of function; secondary and tertiary structures disrupted but primary remains if peptide bonds intact.

  • Enzyme active site

    Region where substrate binds and the reaction occurs.

  • Competitive inhibitor

    Molecule that competes with substrate for binding at the enzyme's active site.

  • DNA vs. RNA bases

    DNA: A, T, C, G; RNA: A, U, C, G.

  • Base pairing rules

    DNA: A pairs with T, G pairs with C; RNA: A pairs with U, G pairs with C.

  • Why DNA is more stable than RNA

    DNA lacks 2′ hydroxyl group making it chemically more stable and is double-stranded allowing repair and replication.

  • Lactase function

    Enzyme that hydrolyzes lactose into glucose and galactose.

  • Lactose intolerance

    Insufficient lactase activity causing undigested lactose to ferment in the large intestine, producing gas and discomfort.

  • Hydrophobic core in proteins

    Nonpolar side chains positioned inside globular proteins away from water, stabilizing tertiary structure.