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Mendelian Inheritance Basics

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  • What is Mendelian inheritance?

    Mendelian inheritance refers to the patterns of inheritance for traits controlled by single genes with clear dominant and recessive alleles, as first described by Gregor Mendel.

  • Who is Gregor Mendel?

    Gregor Mendel was a 19th-century scientist who discovered the fundamental laws of inheritance through experiments with pea plants.

  • What is a gene?

    A gene is a unit of heredity made up of DNA that codes for a specific trait.

  • Define allele.

    An allele is a variant form of a gene that can be dominant or recessive.

  • What is a dominant allele?

    A dominant allele is an allele that expresses its trait even when only one copy is present.

  • What is a recessive allele?

    A recessive allele only expresses its trait when two copies are present (homozygous recessive).

  • What is a genotype?

    Genotype is the genetic makeup of an organism, referring to the combination of alleles it carries.

  • What is a phenotype?

    Phenotype is the observable physical or biochemical characteristics of an organism resulting from its genotype and environment.

  • Explain homozygous genotype.

    Homozygous means having two identical alleles for a particular gene (e.g., AA or aa).

  • Explain heterozygous genotype.

    Heterozygous means having two different alleles for a gene (e.g., Aa).

  • What is a monohybrid cross?

    A monohybrid cross is a genetic cross between individuals differing in one trait controlled by a single gene.

  • What is the typical phenotypic ratio in a monohybrid cross of heterozygotes?

    The typical phenotypic ratio is \(3:1\) dominant to recessive traits.

  • What is the typical genotypic ratio in a monohybrid cross of heterozygotes?

    The genotypic ratio is \(1:2:1\) (homozygous dominant : heterozygous : homozygous recessive).

  • What is the law of segregation?

    The law of segregation states that allele pairs separate during gamete formation, so each gamete carries only one allele for each gene.

  • What is the law of independent assortment?

    The law of independent assortment states that genes for different traits assort independently during gamete formation.

  • What is a test cross?

    A test cross is used to determine the genotype of an individual with a dominant phenotype by crossing it with a homozygous recessive individual.

  • What is a Punnett square?

    A Punnett square is a diagram used to predict the genotypes and phenotypes of offspring from a genetic cross.

  • What does it mean if a trait is autosomal dominant?

    Autosomal dominant traits require only one copy of the dominant allele to be expressed and are located on non-sex chromosomes.

  • What does it mean if a trait is autosomal recessive?

    Autosomal recessive traits require two copies of the recessive allele to be expressed and are located on non-sex chromosomes.

  • What is a carrier in genetics?

    A carrier is an individual heterozygous for a recessive trait who does not show the phenotype but can pass the allele to offspring.