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cells recognize epitopes only when the latter are held by
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21. The Immune System
Functions of T Lymphocytes
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Which statement is FALSE about cytotoxic T cells?
A
They stimulate B cells.
B
They destroy virus-infected cells.
C
They recognize MHC I bound antigens on APCs.
D
They induce apoptosis in infected cells.
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Understand the role of cytotoxic T cells in the immune system. Cytotoxic T cells, also known as CD8+ T cells, are primarily responsible for directly killing infected cells, particularly those infected by viruses.
Review the function of B cells in the immune response. B cells are responsible for producing antibodies and are activated by helper T cells (CD4+ T cells), not cytotoxic T cells.
Examine the interaction between cytotoxic T cells and MHC I molecules. Cytotoxic T cells recognize antigens presented by MHC I molecules, which are found on all nucleated cells, including antigen-presenting cells (APCs).
Consider the mechanism of apoptosis induction by cytotoxic T cells. These cells release perforin and granzymes to induce apoptosis in infected cells, effectively eliminating the threat.
Identify the false statement by comparing the functions of cytotoxic T cells with the options provided. The statement 'They stimulate B cells' is false because cytotoxic T cells do not directly stimulate B cells; this is the role of helper T cells.
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