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Which blood component is primarily responsible for destroying pathogens and removing waste from cells?
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17. The Blood
Introduction To Blood
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In the extrinsic pathway of coagulation, which factor combines with Factor VII to initiate the process?
A
Factor V
B
Factor X
C
Factor III (Tissue Factor)
D
Factor IX
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Understand the extrinsic pathway of coagulation: This pathway is initiated when blood comes into contact with tissue factor (Factor III), which is exposed due to tissue injury.
Identify the role of Factor III (Tissue Factor): Factor III is a membrane-bound protein that is not normally present in the blood but is exposed upon tissue damage.
Recognize the interaction between Factor III and Factor VII: In the extrinsic pathway, Factor III combines with Factor VII to form a complex.
Explain the activation process: The Factor III-Factor VII complex activates Factor X, which is a key step in the coagulation cascade leading to the formation of a blood clot.
Summarize the importance of Factor III: Factor III is crucial for the initiation of the extrinsic pathway, as it triggers the cascade that ultimately results in clot formation.
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