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Trace the pathway taken by a molecule of urea through the kidney from the glomerulus to the renal pelvis if the urea is recycled.
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25. The Urinary System
Renal Physiology Step 2: Tubular Reabsorption
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Which of these substances is primarily reabsorbed from the filtrate in the proximal convoluted tubule?
A
Creatinine
B
Uric acid
C
Glucose
D
Urea
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Understand the function of the proximal convoluted tubule (PCT) in the nephron: The PCT is responsible for the reabsorption of water, ions, and nutrients from the filtrate back into the bloodstream.
Identify the substances listed: Creatinine, Uric acid, Glucose, and Urea. Each of these substances has a different role and behavior in the nephron.
Recall that glucose is a vital nutrient that the body needs to retain, so it is actively reabsorbed in the PCT through specific transport mechanisms.
Recognize that creatinine is a waste product of muscle metabolism and is not reabsorbed; it is excreted in urine.
Understand that while uric acid and urea are partially reabsorbed, they are primarily waste products. Glucose, however, is almost completely reabsorbed in the PCT under normal physiological conditions.
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