The following statements are about the control of chromatin condensation. Select True or False for each. T/F Reducing histone acetylase activity is likely to decrease gene transcription. T/F Mutations that reduce the number of positively charged amino acids on histones should promote open chromatin. T/F Chromatin remodeling complexes add chemical groups to histones. T/F Adding an inhibitor of DNA methylation is likely to reduce gene transcription.

Examine the role of chromatin remodeling complexes and DNA methylation: Chromatin remodeling complexes alter the structure of chromatin not by adding chemical groups to histones, but by repositioning nucleosomes. DNA methylation typically acts to repress gene transcription by attracting proteins that compact chromatin. Therefore, adding an inhibitor of DNA methylation would likely lead to less compact chromatin and potentially increase gene transcription.