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Define immunocompetence and self-tolerance. How is self-tolerance achieved?
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21. The Immune System
Immune Tolerance
Scelta multipla
MHC II proteins are found on __________.
A
antigen-presenting cells
B
helper T cells
C
cytotoxic T cells
D
red blood cells
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Understand the role of MHC II proteins: MHC II (Major Histocompatibility Complex class II) proteins are crucial for the immune response, as they present antigens to certain immune cells.
Identify the types of cells involved in antigen presentation: Antigen-presenting cells (APCs) are specialized cells that display antigens on their surface using MHC II proteins. These include dendritic cells, macrophages, and B cells.
Recognize the interaction between MHC II and T cells: MHC II proteins present antigens to helper T cells (CD4+ T cells), which are essential for initiating the immune response.
Differentiate between helper T cells and cytotoxic T cells: Helper T cells interact with MHC II, while cytotoxic T cells (CD8+ T cells) interact with MHC I proteins, which are found on all nucleated cells.
Eliminate incorrect options: Red blood cells do not have MHC proteins as they lack a nucleus. Cytotoxic T cells interact with MHC I, not MHC II. Therefore, MHC II proteins are found on antigen-presenting cells and interact with helper T cells.
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