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Ch. 11 Fundamentals of the Nervous System and Nervous Tissue
Marieb - Human Anatomy & Physiology 11th Edition
Marieb, Hoehn11th EditionHuman Anatomy & PhysiologyISBN: 9780136874034Non è quello che usi tu?Cambia libro di testo
Capitolo 11, Problema 6

Neuropeptides that act as natural opiates include
a. Substance P
b. Somatostatin and cholecystokinin
c. Tachykinins
d. Enkephalins

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1
Step 1: Understand the term 'neuropeptides' — these are small protein-like molecules used by neurons to communicate with each other. They often modulate pain and other physiological functions.
Step 2: Recognize that 'natural opiates' refer to endogenous substances in the body that bind to opioid receptors and produce effects similar to opiate drugs, such as pain relief.
Step 3: Review the options given: Substance P, Somatostatin and cholecystokinin, Tachykinins, and Enkephalins, and recall their primary functions in the nervous system.
Step 4: Identify which neuropeptides are known to act as natural opiates by binding to opioid receptors and modulating pain — these are typically enkephalins and related peptides.
Step 5: Conclude that among the options, enkephalins are the neuropeptides that act as natural opiates.

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Neuropeptides

Neuropeptides are small protein-like molecules used by neurons to communicate. They modulate brain activity and influence various physiological functions such as pain, mood, and appetite. Unlike classical neurotransmitters, neuropeptides often act over longer distances and times.

Natural Opiates (Endogenous Opioids)

Natural opiates, or endogenous opioids, are neuropeptides produced by the body that bind to opioid receptors to reduce pain and induce feelings of euphoria. Examples include enkephalins, endorphins, and dynorphins, which mimic the effects of opiate drugs like morphine.
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Natural Killer Cells

Enkephalins

Enkephalins are a type of endogenous opioid neuropeptide that bind to opioid receptors in the nervous system to inhibit pain signals. They act as natural painkillers and are involved in regulating nociception and stress responses.
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Match the names of the supporting cells found in column B with the appropriate descriptions in column A.

Column A 

_______ (1) myelinates nerve fibers in the CNS 

_______ (2) lines brain cavities 

_______ (3) myelinates nerve fibers in the PNS 

_______ (4) CNS phagocyte

________(5) helps regulate the ionic composition of CNS extracellular fluid

Column B

a. Astrocyte

b. Ependymal cell

c. Microglial cell

d. Oligodendrocyte

e. Satellite cell

f. Schwann cell

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Assume that an EPSP is being generated on the dendritic membrane. Which will occur?

a. Specific Na⁺ channels will open.

b. Specific K⁺ channels will open.

c. A single type of channel will open, permitting simultaneous flow of Na⁺ and K⁺.

d. Na⁺ channels will open first and then close as K⁺ channels open.

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Biogenic amine neurotransmitters include all but

a. Norepinephrine

b. Acetylcholine

c. Dopamine

d. Serotonin

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An IPSP is inhibitory because

a. It hyperpolarizes the postsynaptic membrane.

b. It reduces the amount of neurotransmitter released by the presynaptic terminal.

c. It prevents calcium ion entry into the presynaptic terminal.

d. It changes the threshold of the neuron.

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a. What is myelin?

b. How does the myelination process differ in the CNS and PNS?

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The anatomical region of a multipolar neuron where the AP is initiated is the

a. Soma

b. Dendrites

c. Axon's initial segment

d. Axon terminals

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