Besides acting as mechanical barriers, the skin epidermis and mucosae of the body have other attributes that contribute to their protective roles. Cite the common body locations and the importance of mucus, lysozyme, keratin, acid pH, and cilia.

Using the letters from column B, match the cell description in column A.

(Note that all require more than a single choice.)

Column A

_____ (1) Phagocytic “cleanup crew”

_____ (2) Releases histamine

_____ (3) Releases perforins

_____ (4) Lymphocyte

_____ (5) Effector cells of adaptive immunity

_____ (6) Antigen-presenting cell

Column B

a. Natural killer cell

b. Neutrophil

c. Dendritic cell

d. Mast cell

e. Cytotoxic T cell

f. B cell

g. Macrophage

h. Helper T cell

i. Basophil

Define immunocompetence and self-tolerance. How is self-tolerance achieved?

The cell type most often invaded by HIV is a(n):

a. Eosinophil

b. Cytotoxic T cell

c. Natural killer cell

d. Helper T cell

e. B cell

Interferons are referred to as antiviral proteins. What stimulates their production, and how do they protect uninfected cells? Which cells of the body secrete interferons?

What is complement? How does it cause bacterial lysis? What are some of the other roles of complement?

Name the five antibody classes and describe where each is most likely to be found in the body.